Flashcards in Cardio Devo Deck (55)
What are the precursor cells for the cardio system?
angioblasts or hmangioblasts; mesenchyme cells within extraembronic and intraembryonic mesoderm
What is a blood island?
aggregates of angioblasts, where they differntiate into endothelial and hemoatopietic stem cells
When are blood islands first observed?
day 17-18 in wall of yolk sac
What is the primary heart derived ffrom?
splanchnic mesoderm, u shaped found cardiogenic cresecent aka primary heart field
Cells from cardiogenic crest migrate into space between foregut endoderm and cardiogenic crest form what?
Remodeling of endothelial plexus results in what?
inner tube with endothelium
What is the primitive heart tumbe?
initial linear heart tube; that is the primitve left ventricle
What is the secondary heart field?
an additional source of cardiac progenitor cells that contribute to the bulbus cordis(primitve right ventricle) outflow region and the primordial atrium the atrioventricular canl and the sinus venosus
What is cardiac endothelium?
the epithelium lining of the lumen of the heart
What is the mycoardium in simple tubular heart?
the outer epithelial tube
What is cardiac jelly?
between endocardium and myocardium; in AVcanal and outflow region.
What are the swellings in teh cardiac jelly?
endocardial cushions; either bulbar or conotruncal ridges
What ist he epicardium?
derived from proepicardial organ a cluster of coelomic epithelial cells adjacent to sinus venosus
underlying visceral pericardium; also contribute to formation of coronary vessels
Venous inflwo at the venous pole results in what?
several venous channels enter the sinus venosus of the primitive heart; umbilical veins contain placental blood
common cardinal veins
What do vitelline veins do
contain oxygen poor blood from gut
What do common cardinal veins do?
contain oxygen poor blood from head and trunk
Which direction does the heart loop to?
the heart almost always loops to the right
A lack of proper looping results in what?
failure of complete looping results in retention of embryonic pattern of blood flow through the heart; double inlet left ventricle and double outlet right ventricle
What days does blood flow occur?
begins at day 20-22 and by day 26 becomes unidirectional
What forms the definitve right atrium?
primordial right atriuma dn portions of the sinus venosus
What does the proximal portion of the right anterior cardinal vein become?
superior vena cava
What becomes the terminal segment of the inferior vena cava?
cranial portion of the right vitelline vein
What is hte ridge of tissue to form the junction between smootha nd trabeculate portions of definitvie right atrium?
What is teh coronary sinus derived from?
left sinus venosus
What is derived from teh right sinus valve?
valve of the IVC
valve of CS
What is the smooth area of right atrium derived from?
absorbed right SV
What is the Inferior vena cava (terminal segment) derived form?
right vitelline vein
What is the superior vena cava derived from?
right common cardinal vein
What is the appendage (trabeculate poriton derived from?