Cardiology Flashcards Preview

Paediatrics > Cardiology > Flashcards

Flashcards in Cardiology Deck (86):

What is the ductus arteriosus?

Connects the pulmonary artery to the aorta so that blood doesn't flow to the lungs, closes within first few hours or days


What % of congenital heart defects are picked up antenatally? And when?

70% at 18-20 week anomaly scan


What is the most common presentation of congenital heart disease - complication of presentation?

A heart murmur - however 30% of children will have an innocent murmur at some point which is present in a normal heart


What are the hallmarks of an innocent ejection murmur?

4 s's
aSymptomatic patient
Soft blowing murmur
Systolic murmur only - not diastolic
left Sternal edge - no radiation
Also - normal heart sounds with no added sounds and no parasternal thrill


What can be causes of innocent murmur

Anaemia or febrile illness due to increased cardiac output


Main cause of heart failure in first week of life

Coarctation of the aorta


What can be important in maintaining arterial perfusion in coarctation of the aorta

Right to left flow of blood via the arterial duct = duct dependant systemic circulation
If the duct closes then severe acidosis, collapse and death


Main cause of heart failure after first week of life - mechanism and symptoms (when?)

Left to right shunt. As weeks go on, pulmonary vascular resistance falls, progressive increase in left to right shunt and increase pulmonary blood flow
Causes pulmonary oedema and breathlessness - about 3 months of life


What will happen if left to right shunt goes untreated

Children will develop Eisenmenger syndrome - irreversibly raised pulmonary vascular resistance as resistance rises in response to the left right shunt
Shunt is now from right to left due to raised pulmonary pressure and TEENAGER is blue


Treatment of Eisenmenger syndrome

Only really heart lung transplant - medication is available to palliate symptoms


Causes of neonatal heart failure other than coarctation of the aorta x3

Hypoplastic left heart syndrome
Critical aortic valve stenosis
Interruption of the aortic arch


Causes of heart failure in infants

Due to high pulmonary flow therefore ventricular septal defect, atrioventricular septal defect and large persistent ductus arteriosus


Causes of heart failure in older children

Rheumatic heart disease and cardiomyopathy


When can peripheral cyanosis occur? X3

If child is cold, unwell from any cause or due to polycytheamia


When does central cyanosis occur? What level of reduction needs to be present for its identification

Due to fall in arterial blood oxygen tension
Can only be recognised if concentration of reduced haemoglobin in blood exceeds 5g/dl
Therefore less pronounced if child is anaemic


What is persistent cyanosis in an otherwise well child a sign of?

Structural heart disease


Presentation of right to left shunt symptom wise

Blue child


Presentation of left to right shunt symptom wise

Breathlessness or asymptomatic


3 causes of left to right shunt

ASD, VSD, or persistent ductus arteriosus


Two types of ASD and incidence

Secundum ASD (80%)
Partial atrioventricular septal defect


What is Secundum ASD

Defect in centre of atria where foramen ovale is


What is partial AVSD?

Defect of AV septum involving atrial septum and av valves
Also 3 leaflet defect in left av valve with regurgitant leak


Symptoms of ASD

Asymptomatic or recurrent lung infections/wheeze
Arrhythmias from 4th decade onward


Physical signs of ASD on auscultation

Ejection systolic murmur best heard at left Sternal edge because increase blood flow over pulmonary valve


Physical sign of partial AVSD on auscultation

Apical pan systolic murmur due to regurgitation through AV valve


Signs of ASD and AVSD on chest X-ray x3

Cardiomegaly, increased pulmonary vascular markings, enlarged pulmonary arteries


ECG signs with Secundum ASD

Partial right bundle branch block is common
Right axis deviation due to right ventricle enlargement


ECG in partial AVSD

Superior QRS complex - mainly negative in avF - because defect is near av node therefore displaced node conducts to the ventricles superiorly


Management of Secundum ASD

Cardiac catheterisation with insertion of occlusion device usually done 3-5 years of age


Management of partial AVSD

Surgical correction. - usually done 3 years of age


What % of congenital heart disease is due to VSD



Symptoms and signs of small VSD (what size?)

No symptoms and loud pan systolic murmur at lower left sternal edge (louder the murmur, smaller the defect)
Smaller than 3mm


Investigations in small VSD

Normal ecg normal X-ray - echo will show defect


Management of small VSD

They will close spontaneously


Symptoms of large VSD x4

Heart failure
Breathlessness and failure to thrive in 1 week old
Recurrent chest infections


Signs of large VSD x 5

Tachycardia, tachypnoea and enlarged liver from heart failure
Active precordium
Soft pansystolic murmur or no murmur
Apical mid-diastolic murmur (increased flow across mitral valve with return of blood through lungs)
Loud pulmonary second sound from raised pulmonary arterial pressure


Chest X-ray with large VSD

Enlarged pulmonary arteries
Increased pulmonary vascular markings
Pulmonary oedema


What is the foramen ovale?

Hole between the right and left atrium. As the lungs are not in use, pressure in them is high and blood flow is low, therefore pressure is low in the left atria...also pressure in the right atria is high as it receives all the blood flow from the placenta. Therefore hole stays open. When lungs start breathing, blood flow to lungs increases and pressure in right atria drops as no more placenta therefore pressure higher in left atria and foramen closes


ECG in large VSD

Biventricular hypertrophy by 2 months of age


Management of large VSD

Treat heart failure with diuretics and captopril
Additional calorie intake
Surgery at 3-6months to prevent Eisenmenger syndrome


Two causes of patent ductus arteriosus

Congenital heart defect or prematurity (if in preterm infant)


Clinical features of patent ductus arteriosus with additional features if it's a large duct

Continuous murmur upper left sternal edge (always a murmur because pressure is lower in the pulmonary artery than in the aorta throughout the cardiac cycle)
Pulse pressure increased causing a bounding or collapsing pulse
Large duct - heart failure and pulmonary hyper tension


Investigations in patent ductus arteriosus

X-ray and ECG usually normal
However if large the signs are the same as with large VSD


Management of patent ductus arteriosus

Closure with coil or occlusion device via cardiac catheterisation at 1 year of age
Occasionally surgical ligation


What sort of heart disease does right to left shunts cause

Cyanotic heart disease - present with cyanosis and O2 sats


Diagnostic test of cyanotic heart disease

Hyperoxia (nitrogen washout) test
Place infant in 100% oxygen for 10min - if right radial artery pao2 from blood gas remains low diagnosis can be made (if lung disease and persistent pulmonary hypertension of newborn have been excluded)


Management of neonatal cyanotic heart disease

Start prostaglandin infusion - maintain duct patency as they are duct dependant


What is most common cause of cyanotic heart disease and features x4

Tetralogy of fallot
- large VSD
- overriding aorta with respect to ventricular septum
- sub pulmonary stenosis causing right ventricular outflow tract obstruction
- right ventricular hypertrophy as a result


When are most tetralogy of fallot diagnosed?

Most are diagnosed antenatally or following identification of murmur in the first 2 months of life
Cyanosis may not be obvious at this stage - although a few present with severe cyanosis in first few days of life


Classical description of symptoms of tetralogy of fallot

Severe cyanosis
Hypercyanotic spells (irrability, crying, breathlessness and pallor) and squatting on exercise
Developing late in infancy
- now rarely seen in developed countries


Murmur in tetralogy of fallot

Loud harsh ejection systolic murmur at left Sternal edge from day 1 of life
With increasing outflow obstruction (due to muscular hypertrophy) murmur will shorten and cyanosis with increase


Chest X-ray in tetralogy of fallot

May have pulmonary artery 'bay' - concavity on left heart border where artery and outflow tract would normally be
Decreased pulmonary vascular markings


Management of tetralogy of fallot

Surgery to remove obstruction and close VSD at around 6 months of age
Very cyanosed infants may require shunt in the meantime eg. from subclavian artery to pulmonary artery


What does transposition of the great arteries cause

Right to left shunt


What is transposition of the arteries anatomically

Pulmonary artery is connected to the left ventricle and aorta to the right ventricle therefore oxygenated blood returns to the lungs and deoxygenated blood returns to the body
Unless there is a defect such as VSD, ASD or pda this is not compatible with life


Symptoms/presentation of transposition of the great arteries

Cyanosis - usually at 2 days of life when closure of pda leads to decreased mixing


Auscultation in transposition of great arteries

Usually no murmur but may be systolic murmur due to stenosis of left pulmonary outflow tract


Management of transposition of great arteries

Maintain ductus arteriosus - prostaglandin infusion
Balloon atrial septostomy may be life saving
Most need surgery - arterial switch procedure within first few days of life
- transected above the valves and switched over
Transfer coronary arteries over to new aorta


Which syndrome cause common mixing cardiac problems

Complete atrioventricular septal defect and complex congenital heart disease (such as mitral atresia, tricuspid atresia)
Breathless and blue


When is complete AVSD commonly seen?

Down's syndrome


What are the defects present in complete AVSD

5 leaflet av valve - defect stretches all across the av junction and tends to leak


Which lesions cause outflow obstruction in a well child x3

Aortic stenosis, pulmonary stenosis, adult-type coarctation of the aorta


Features and symptoms of aortic stenosis

Can occur in association with mitral stenosis and coarctation of the aorta
Most have asymptomatic murmur but may present with chest pain on exertion, reduced exercise tolerance or syncope


Signs of aortic stenosis

Ejection systolic murmur - maximal at left Sternal edge and radiating to neck
Small volume, slow rising pulses
Apical ejection click


Features of pulmonary stenosis

Most are asymptomatic

Ejection systolic murmur best heard upper left Sternal edge
If severe might be right ventricular hypertrophy and heave


Features of adult-type coarctation of the aorta

Not duct dependant - gradually becomes more severe over many years


Features of coarctation of the aorta

Systemic hypertension in the right arm
Ejection systolic murmur at upper sternal edge
Collaterals heard with continuous murmur at the back
Radio femoral delay


Adult type coarctation of the aorta on X-ray

Rib notching - due to development of large intercostal arteries running under ribs to bypass obstruction
'3' sign with visible notch in the descending aorta at site of coarctation


Adult type coarctation of the aorta on ecg

Left ventricular hypertrophy


Causes of outflow obstruction in a sick child

Coarctation of the aorta
Interruption of the aortic arch
Hypoplastic left heart syndrome


How do sick children with outflow obstruction present?

Sick with heart failure and shock in neonatal period
Prostaglandin should be commenced straight away


When do children with coarctation of the aorta present?

Usually at 2 days of age with acute circulatory collapse when the da closes


Physical signs in children with coarctation of the aorta

Severe heart failure
Absent femoral pulses
Severe metabolic acidosis


Management of coarctation of the aorta

Surgical repair


What is interruption of aortic arch

Aorta does not continue to lower body - instead the connection to the pulmonary artery becomes the vessel and continues this way, there is also a VSD therefore cardiac output is maintained via left-to right flow across duct


What is Hypoplastic left heart syndrome?

Underdevelopment of the left side of the heart - surgical treatment with complicated operation


What is the most common childhood arrhythmia

Supra ventricular tachycardia


Treatment of supraventricular tachycardia in neonate

Very fast heartbeat (250-300bpm) therefore need circulatory and respiratory support
Vagal stimulating manoeuvres (carotid sinus massage or cold ice pack to face) successful in 80%
IV adenosine or cardio version if that fails
Maintenance with flecainide or sotalol
Resting ECG will remain normal but 90% will have no further attacks after infancy therefore treatment can be stopped at age 1


What mostly causes syncope in teenagers

Neurocardiogenic, situational, orthostatic or ischaemic causes


Features of a cardiac cause of syncope

Symptoms on exercise
Family Hx of sudden unexplained death


What age usually affected by rheumatic fever

5-15 years
Following group a b-haemolytic strep -2-6 weeks later


Most common cardiac sequela of rheumatic fever

Mitral stenosis, can also get carditis, also less frequently aortic, tricuspid and rarely pulmonary disease


Acute management of rheumatic fever heart disease

Aspirin for inflammation and bed rest
If aspirin doesn't work then corticosteroids
Antibiotics if evidence of persisting infection


Management following resolution of acute rheumatic fever episode

Prophylaxis with monthly penicillin injections
Up until the age of 18-21
Severity of episodes influences length of treatment


What are all children with congenital heart disease (except for Secundum ASD) at high risk of

Infective endocarditis - highest risk with turbulent jet of blood - eg. VSD, coarctation of the aorta and persistent DA


Most common organism for infective endocarditis

A-haemolytic strep
Treat with high dose penicillin + amino glycoside given IV for 6 weeks