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Cardiomyopathies Flashcards

(45 cards)

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0
Q

Organic solvent that causes DCM

A

Toluene

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1
Q

3 chemo therapies that can cause DCM

A 
Daunoribicin
Doxorubicin
Sunitinib
Trastuzumab
Cyclophosphamide
Bleomycin
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2
Q

Party drugs that can cause DCM

A

ETOH

Cocaine

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3
Q

Heavy metals that can cause DCM

A

Mercury
Lead
Cobalt

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4
Q

Antiretrovirals that can cause DCM (3)

A

Zidovudine
Didanosine
Zalcitabine

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5
Q

Time frame for peripartum CM

A

Last month of pregnancy to 5 mo’s after

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6
Q

Risk factors for peripartum CM

A 
Age> 30
Multiparity
AA
h/o preeclampsia or postpartum HTN
cocaine
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7
Q

Drug of choice in pregnant women instead of ACEI

A

hydralazine

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8
Q

Population at risk of Takotsubo

Percent risk of ventricular arrhythmias?

A

Postmenopausal women

15%

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9
Q

Recurrence rate for Takotsubo

A

4%

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10
Q

Bugs causing HIV focal myocarditis

A 
HIV
CMV
EBV
coxsackie
Toxoplasma
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11
Q

Inheritance pattern of muscular dystrophies.

Which is worse (Becker’s or Duchenne’s) for CM?

A

X-linked

Becker’s

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12
Q

When should you suspect anthracycline induced CM (daunorubicin)?
Risk factors

A

Dose dependent> 550mg/m2
3-12 months after.
Can occur upto 10y later
DM, HTN,

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13
Q

If high doses of daunorubicin needed,what med to give to avoid CM?

A

Dexrazoxane, ACEI, BB

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14
Q

Difference in LVEDD b/w HCM and athlete

A

HCM: LVEDD <45

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15
Q

What type of activity is OK with HCM?

A

Low level

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16
Q

3 factors making SAM worse in HOCM

A

Increased contraction
Decreased resistance (vasodilator)
Decreased volume

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17
Q

Preferred Rx in HOCM (myomectony vs. septal ablation)

A

Myomectony

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18
Q

LV wall thickness in HOCM

19
Q

7 risk factors are needed to place ICD in HOCM. Not including VT/VF/SCA, what are the 5 other risk factors?

Study These Flashcards
A 
Fam hx of SCD
LV thickness > 3cm
Recent unexplained syncope
NSVT
BP drop w/ exercise
20
Q

Do steroids help for myocarditis

21
Q

Treatment for myocarditis with reduced LV function

22
Q

Will you see myofiber necrosis on biopsy of myocarditis?

23
Q

8 common viral Pathogens causing myocarditis

Study These Flashcards
A 
CMV
Coxsackie B
Hep C
Echo
Adeno
Parvovirus 
Influenza
24
Which biomarkers are more sensitive in myocarditis?
Trops
25
What do you see on MRI of myocarditis
Late gad
26
Do you do routine bx for myocarditis?
No
27
Rx and followuo of myocarditis
HF meds | Echo at 1, 6, and 12
28
Giant cell myocarditis is progressive and often fatal, Rx?
Thymoglobulin Corticosteroids Calcineurin inhibitors
29
Giant cell myocarditis- which immune cell? | Is biopsy high yield?
T cell | Yes
30
Acute phase treatment of chagas HF?
Nitrofurtimox
31
3 cardiac issues Lyme will cause
DCM HB (arrhythmias) Myocarditis
32
Lyme carditis bug and treatment and serologies
IgM Ceftriaxone Bordelaise burgdorferi
33
2 things to remember about lupus CM
Can wax and wane- treat the lupus flare | Systolic and diastolic dysfxn
34
What does cardiac bx show in lupus?
Mononuclear cells
35
Fever, rash, peripheral eos and eos on cardiac bx. | Dx and Rx?
Hypersensitivity Myocarditis | Remove any offending meds and give steroids
36
Hoarseness, macroglossia, neuropathy, proteinuria, swallowing disorder, RUQ tenderness. Exam: JVD w/ prom x and y descent, pleural effusions, hepatomegaly, edema, KUSSMAUL's and S3 & S4. Dx, echo, EKG, Bx findings.
Cardiac amyloid Speckled appearance, LVH low voltage Apple green birefringence
37
Management of transthyretin gene mutant cardiac amyloid
Family genetic testing | Live transplant
38
Which amyloid has better prognosis (senile or AL)?
Senile
39
2 studies that are high yield to diagnose amyloid
MRI (late gad) | Bx
40
Nuclear and echo findings with cardiac sarcoid
Regional WMA | perfusion defect
41
Do you get late gad enhancement on MRI with cardiac sarcoid?
Yes
42
Exact treatment for cardiac sarcoid
Corticosteroids 1mg/kg we'd x 3 months | Low threshold for ICD
43
Common secondary cause for cardiac hemochromatosis
Multiple transfusions
44
How to diagnose cardiac hemochromatosis? Rx?
T2* MRI | chelation/phlebotomy

Cardiology (32 decks)

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