cardiovascular 3 Flashcards

1
Q

What can cardiac arrhythmia be divided into

A

tachycardia
bradycardia

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2
Q

Give examples of tachycardia

A

Sinus tachycardia
Supraventricular tachycardia
Ventricular tachycardia
Atrial fibrillation
Ventricular fibrillation

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3
Q

What is sinus tachycardia

A

Heart rate of above 100 beats per min with ECG showing a normal P wave before each QRS complex

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4
Q

When does sinus tachycardia occur

A

Normal response to exercise

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5
Q

What can sinus node disease lead to

A

Both bradycardia and tachycardia due to malfunction of the Sino atrial node

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6
Q

What is supra ventricular tachycardia

A

abnormal tachycardias originating in or above the AV node

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7
Q

Where can supraventricualr tachycardia result from

A

May arise from the atria where a P wave will still be seen or from the AV node itself

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8
Q

When does a ventricular tachycardia arise

A

Arises within the ventricle because the electrical impulse spreads from the abnormal focus directly through the heart muscle

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9
Q

What is atrial fibrillation

A

atrial activity becomes completely disorded with constant electrical activity throughout the atria and loss of co ordinated atrial contraction

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10
Q

what can be the risk during atrial fib

A

increase risk of clot formation and therefore stroke

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11
Q

Describe the ECG of a patietn with atrial fibrillation

A

no P wave

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12
Q

what medication do we use for atrial fib

A

previously warfarin but recently DOACS

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13
Q

Give examples of some bradycardias
A
Sinus bradycarida
Atrio ventricular block
Sinus node

A

Sinus bradycarida
Atrio ventricular block
Sinus node disease
Cardiovascular reflex disorders

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14
Q

WHAT medications can we use for anti dysrhythmic medicines

A

class 1: procainamide, quinidine, lidocaine
class 2: beta blockers
class 3: amiodarone
class 4: calcium channel blockers
glycosides

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15
Q

what LA should be avoided if on anti dysthymics

A

bupivicaine

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16
Q

What can sinus bradycardia be caused by

A

Drugs or hypothyroidism

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17
Q

What can cadiovasuiclar reflex disorders result in

A

Syncope due to transient bradycardias

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18
Q

What clinical assessments do you need to make at the time of suspected arrhythmia

A

Basic life support
Pulse
Blood pressure
ECG

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19
Q

Why is digoxin given to tachycardias patients

A

To control the ventricular rate in atrial fibrillation

20
Q

Why is Amiodarone given to tachycardias patients

A

Can sometimes revert atria fibrillation to sinus rhythm

21
Q

How are drugs used to treat arrhythmia classified

A

Can be classified by what they act on
Classified using the Vaughan Williams classification

22
Q

Talk through the mechanisms of action of cardiac glycosides

A

They inhibit the membrane bound sodium potassium ATPase which result sin an increase in intracellular sodium
intracellular calcium rises producing an increase in contractility

23
Q

What impact can digoxin have on oral structures

A

pain similar to trigeminal neuralgia in the lower part of the face

24
Q

What is digoxin toxicity perciprated by

A

hypokalaemia

25
Q

Give examples of drugs in dentistry that can produce hypokalaemia

A

LA with adrenaline

26
Q

Give examples of drugs that can increase the plasma concentration of digoxin

A

NSAIDS
Erythromycin
Itraconazole

27
Q

What can class I antiarrhythmics be further divided into?

A

class I A
class I B
class I c

depending on how much they bind to sodium channel and the effect on cardiac action potential

28
Q

What do class I a drugs do

A

prolong the action portenail

29
Q

What do class I b drugs do

A

shorten the action potential

30
Q

What do class I c drugs do

A

have little/no effect upon action potential

31
Q

the mechanism of action of class I membrane stabilising drugs

A

act on sodium channel blockers
the binding site for these drugs is only available when the sodium channel is in the open or refractory state
Accessibility to the target is governed by the rate of openign of the channel

32
Q

what effect can class I membrane stabilising drugs have on oral structures and dental management

A

They may produce angioedema that can effect the lips tongue and floor of the mouth

33
Q

what are some lifestyle adjustments patients can make

A

diet
limit alchohol
exercise
smoking cessation
flu vaccine

34
Q

what causes polyuria

A

diuretics

35
Q

what causes dry mouth

A

diuretics
ace inhibitors
beta blockers

36
Q

what causes glossitis

A

ace inhibitors

37
Q

what causes erythema multiform

A

ace inhibitors

38
Q

what causes lichenoid reactions

A

thiazide
diuretics
ace inhibitors
beta blockers

39
Q

what causes peri oral numbers

A

beta blockers

40
Q

what causes bone marrow supression

A

captopril

41
Q

what causes low platelets

A

prazocin
hydralazine
amiofarone

42
Q

what medications can interact with NSAIDS

A

ace inhibitors
antitension receptor blockers
beta blockers
digoxin

43
Q

what can interact with LA

A

diuretics
calcium channel blockers
beta blockers
class 1 antiarrhymics
digoxin

44
Q

what interacts with erythromycin

A

anti arrhythmic

45
Q

what interacts with some anti fungals

A

anti arrhythmic

46
Q

what causes taste disturbance

A

ace inhibitor
angiotensin receptor blockers
calcium channel blockers