Cardiovascular Drugs Flashcards
(20 cards)
The Circulatory System
The system that contains the heart and the blood vessels and moves blood throughout the body.
2 primary functions of The circulatory system
1:delivery of oxygen, nutrients, hormones, electrolytes, and other essentials to cells and
2: removal of carbon dioxide and metabolic wastes from cells. In addition, the system helps fight infection.
The heart
-Is the pump that moves blood through the arterial tree.
Arteries
-Transport blood under high pressure to tissues.
Arterioles
-Control valves that regulate local blood flow.
Arterioles
-Control valves that regulate local blood flow.
Capillaries
-Sites for exchange of fluid, oxygen, carbon dioxide, nutrients, hormones, and wastes.
Venules
-Collect blood from the capillaries.
Veins
-Transport blood back to the heart. In addition, veins serve as a major reservoir for blood.
Determinants of Cardiac Output
-Heart rate
-Stroke volume
-Preload
-Afterload
Heart rate
-Controlled by the ANS
Stroke volume
-Determined by 1) myocardial contractility (force with which the ventricles contract),2) cardiac afterload, 3) cardiac preload
Preload
-Amount of tension (stretch) applied to a muscle before contraction = force of venous return
Afterload
-Load against which a muscle exerts its force = arterial pressure that the left ventricle overcomes to eject blood
Hypertension
-A persistent systolic pressure of greater than 140mmHg and/or a diastolic pressure of greater than 90mmHg
Blood Pressure
-The product of cardiac output and systemic vascular resistance
Cardiac output
-Amount of blood ejected from the left ventricle and measured in Lpm
SVR (systemic vascular resistance )
-Resistance to blood flow that is determined by the diameter of the blood vessels and vascular musculature
Goal of Antihypertensive Therapy
-Reduction of cardiovascular and renal morbidity and mortality
-achieve a blood pressure of less than 140/90mmHg and for patients with hypertension and diabetes, less than 130/90mmHg
Diuretics
-Drugs that accelerate the rate of urine formation that results to the removal of sodium and water from the body