Endocrine Drugs

Question 1

The Endocrine System

Answer 1

The glands and organs that make hormones and release them directly into the blood so they can travel to tissues and organs all over the body.

Question 2

Hormones

Answer 2

Chemical substance produces in the body that controls and regulates the activity of certain cells or organs.

Question 3

3 more common hormones

Answer 3

-Peptide hormones
-Steroid hormones
-Amine hormones

Question 4

Hormones that can found in Posterior Pituitary and their target and effects

Answer 4

H- ADH(Antidiuretic hormone) or Vasopressin
T- Kidney and arterioles
E- Inhibits urine production: vasoconstriction

Question 5

Hormones that can found in Anterior Pituitary Gland and their target and effects

Answer 5

H- Growth Hormones
T- Liver. Adipose Tissue
E- Increase secretion of IGF-I (Insulin-like growth factor 1) for bones and muscle growth

Question 6

Hormones that can found in Thyroid and their target and effects

Answer 6

H- Thyroid hormone
T- Various Tissues
E- Regulation of metabolic rate and promotion of body growth

Question 7

Hormones that can found in Adrenal Cortex and their target and effects

Answer 7

H- Aldosterone
T- Kidneys
E- Regulates the body’s sodium balance

H- Cortisol
T- Various tissues; liver
E- Release of glucose, amino acids and fatty
acids into the blood

Question 8

Hormones that can found in Adrenal Medulla and their target and effects

Answer 8

H- Adrenaline
T- Various tissues - heart, blood vessels and bronchioles
E- Increase in BP, blood glucose and bronchodilation

Question 9

Hormones that can found in Pancreas and their target and effects

Answer 9

H- Insulin and Glucagon
T- Various Tissues - liver and fat cells
E- Regulation of blood glucose

Question 10

Drugs Acting on Anterior Pituitary Gland

Answer 10

Growth hormone E.g Somatrem [Protropin], Somatropin [Humatrope]

Question 11

Contraindications and Adverse Effects of Growth hormone E.g Somatrem [Protropin], Somatropin [Humatrope]

Answer 11

C- Hypersensitivity, Closed Epiphyses
AE- antibody formation, lipoatrophy, diabetogenic, local irritation at injection site, fluid retention

Question 12

Somatostatin Agonists

Answer 12

-Growth hormone inhibiting hormone [GHIH]

C-Hypersensitivity, Pregnancy, Lactation
AE- GI distress, constipation/ diarrhea, flatulence, nausea, acute cholecystitis

Question 13

Drugs Acting on the Posterior Pituitary Gland and their indication, contraindication and adverse effects

Answer 13

-ADH [Vasopressin], PitressinSynthetic, Desmopressin

I- Diabetes Insipidus [IV, Nasal Spray]; Hemorrhage, Post-operative abdominal distention
C- Hypersensitivity, Vascular Disease, Pregnancy, Lactation
AE- Water Intoxication [drowsiness, light-headnedness, headache, coma, convulsions]
Hangover Effect: tremor, sweating, vertigo, headache

• OXYTOCIN

I- Used to initiate labor, promote delivery of placenta and control post-partum hemorrhage, Used to promote breastmilk let-down
C- hypersensitivity, cardiovascular spasm, hypotension, N&V
AE- non-vertex fetal presentation, fetal distress

Question 14

NURSING PROCESS

Answer 14

-Obtain baseline v/s, I&o, height and weight
-Assess for allergic reactions
-Monitor patient fluid volume
-Monitor nasal passages if given intranasally
-Monitor blood sugar