Carlsson et al

Question 1

Aim

Answer 1

to review studies on the relationship between levels of NT and sz - specifically dopamine and glutamate

• also wanted to explore possibility of new antipsychotics for those currently resistant

Question 2

Procedure/review

Answer 2

meta analysis:
reviewed own research on rodents, Parkinson’s patients, PET scans and effect of recreational drugs

Question 3

Results

Answer 3

1. increased DA leads to sz symptoms, but not everyone with increased DA will experience them
2. low glutamate leads to sz symptoms
3. different symptoms can be treated with different antipsychotics

Question 4

Conclusion

Answer 4

research needs to be conducted into developing drugs to treat sz that consider other NT

Question 5

Strengths

Answer 5

• reliability - lot of research used reliable methods such as PET scans which objectively measure brain activity
• usefulness - can help with development of treatment that are tailored to each individual - more people treated

Question 6

Weakness

Answer 6

rel + val - no way of knowing rel or val of data as C used secondary data - results and conclusions may not be useful