CARTILAGE Flashcards

(39 cards)

1
Q

Tissue =

A

Cells and Extracellular matriX

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2
Q

ECM OF CARTILAGE IS RICH IN

A

chondroitin sulfate

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3
Q

fibers of cartilage, what collage

A

type II collagen

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4
Q

one of the glycosaminoglycan that allow cartilage to withstand compression

A

chondroitin sulfate

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5
Q

Synthesize the fibers and ground substance

A

CHONDROCYTES

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6
Q

Bone, tendon, skin, dentin

A

type 1 collagen

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7
Q

type 1 collagen funciton

A

resistance to tension

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8
Q

collagen type 2 tissues

A

cartilage, vitreous body

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9
Q

type 2 collage is _______ not easily seen under the miscroscope

A

highly refractile

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10
Q

function of collagen type 2

A

resistance to pressure

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11
Q

collagen type 3 tissue

A

reticular fibers

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12
Q

collagen type 3 function

A

supports parenchyma of organs

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13
Q

collagen type 4 tissues

A

basement membrane

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14
Q

collagen type 4 funciton

A

sheet-forming collagen

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15
Q

collagen type 7 tissue

A

basementmembrane

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16
Q

collagen typ e7 function

A

anchors basal lamina to reticular lamina

17
Q

The matrix immediately surrounding the lacunae
is more intensely BASOPHILIC

A

TERRITORIAL MATRIX

18
Q

This is due to the masking of the collagen fibers
by the high concentration of the
____________ in the ground substance. (basophilia)

A

glycosaminoglycans

19
Q

retains water thus allowing
cartilage to act as shock absorber.

A

Ground substance

20
Q

why prone to OA?

A

chondrocyte no longer produce ECM

21
Q

FUNCTIONS OF THE CARTILAGE

A

Shock absorber
Provide framework and support
Protects underlying tissue
Provides flexibility
Provides template for bone formation

22
Q

Dense irregular connective
tissue covering of
cartilages

A

perichondrium

23
Q

perichondrium 2 layers

A

fibrous
chondrogenic

24
Q

Chondroblasts in perichondrium differentiate into chondrocytes, start producing matrix, and add to existing cartilage beneath the perichondrium.

A

Appositional Growth:

25
proliferation and hypertrophy of existing chondrocytes. It occurs within the cartilage. Chondrocytes will divide (mitosis) producing isogenous aggregates that deposites ECM making chondrocytes move away from each other.
Interstitial growth
26
Hyaline: Nuclei: formation:
Elliptical shape at periphery isogenous cell groups
27
Similar to hyaline cartilage except that is contains abundant network of elastic fibers
ELASTIC CARTILAGE
28
elastic cartilage is elastic fibers +
collagen II
29
Elastic cartilage is found in
Ear (auricle) Epiglottis Eustachian tube
30
skinfold of the ear is made up of what epithelium
stratified squamous keratinized epithelium
31
ntermediate between dense connective tissue and hyaline cartilage
FIBROCARTILAGE
32
Rich in collagen 1
FIBROCARTILAGE
33
toughest among all collagen
collagen 1
34
Fibroblast: Chondrocytes occur singly or ____ isogenous aggregates
aligned
35
_____immediately surrounding the chondrocytes has type 2 collagen
Matrix
36
Isogenous aggregates of chondrocytes are separated by _____ collagen fibers
type 1
37
Chondrocytes are ________ and with ___ metabolic rate
immobile; low
38
extensive damage causes the perichondrium to produce a scar of _____ connective tissue
dense
39
outer fibrous layer will cause the _________ to deposit collagen fibers in the collagen tissue forming a scar
fibroblast