Cartilage Flashcards
What creates and maintains the extracellular matrix of Cartilage?
Chondrocytes
What are some of the properties of the extracellular matrix?
Permits readily diffusion due to large ratios of GAGs
Resilient to repeated application of pressure
What are the 3 types of cartilage?
Hyaline
Elastic
Fibrocartilage
What is the structure of Hyaline cartilage?
Matrix has proteoglycans, hyaluronic acid and type II collagen.
What is the structure of Elastic cartilage?
Matrix containing preteoglycans, hyaluronic acid, type II collagen, elastic fibres and elastic lamellae
What is the structure of Fibrocartilage?
Matrix has preteoglycans, hyaluronic acid, type II collagen, type I collagen
What cell types are present in Hyaline cartilage?
Chondrocytes (singly or in small groups called Isogenous groups)
What is Perichondrium?
Lines Hyaline cartilage and gives rise to Chondroblasts that go on to make extracellular matrix and chondrocytes.
What is Appositional growth?
Where the extracellular matrix of Hyaline cartilage grows from the periphery due to the Perichondrium forming Chondroblasts
What is Interstitial growth?
Deposition of matrix by Isogenous groups of Chondrocytes
Where is there no Perichondrium on Hyaline cartilage?
Articulating surfaces
Epiphyseal growth plates
Where can you find elastic cartilage?
In the pinna (external ear)
Epiglottis
What are the cell types in Fibrocartilage?
Chondrocytes (tend to be arranged in rows)
Fibroblasts
It is a mixture of dense regular connective tissue and Hyaline cartilage
Does Fibrocartilage have a Perichondrium?
No
Where can you find Fibrocartilage?
Intervertebral discs
Menisci of the knee joint
Pubic symphysis
