CBC Flashcards
(66 cards)
What does a CBC include?
- WBC
- RBC
- Hemoglobin, hematocrit, red cell indices
- platelets
What’s a normal total WBC?
4500-11000
What’s a normal total WBC for <2 years ?
6200-17000
What’s a normal total WBC for infants?
9000-30000
T/F: elderly may not have a high white count in setting of infection
t
What are critical WBC values?
<2000, >40,000
What do these cause
- bone marrow failure
- viral infection
- aplastic anemia
-vitamin deficiencies
- B12 or iron deficiencies
-autoimmune diseases
-drug toxicity
decreased WBC (leukopenia)
What do these cause
-inflammation
-infection
-leukemia
-malignancies
-vascular conditions
-tissue necrosis
-steroids*
-stress from trauma
-seizures/uncontrolled shivering
-thyroid storm
-dehydration
elevated WBC (leukocytosis)
____ can mimic leukemia
sepsis
Differential count = % of each type of leukocyte present
including granulocytes + nongranulocytes
First responders to bacterial infections, elevated in bacterial infections, trauma, or stress
neutrophils
Elevated in allergies, asthma, or parasitic infections
eosinophils
involved in inflammatory responses, rarely elevated but seen in CML - allergens, parasites, pathogens
basophils
elevated in viral infections, chronic inflammation, certain cancers
lymphocytes
engulf pathogens, increased in chronic infections, TB, and certain leukemias
monocytes
Neutrophils are produced in ____ days, only live for ____ hours
7-14 days, 6 hours
When are neutrophils elevated? (neutrophilia)
inflammation (RA, thyroiditis), cushing syndrome
When are neutrophils decreased (neutropenia)?
drugs, chemo/radiation, anaplastic anemia, viral infections (measles, hepatitis, influenza)
Leukocytosis + neutropenia =
SEPTIC BILLS
Severe bacterial infection
Exercise
Postsplenectomy
Trauma
Inflammation
Corticosteroids
Burns
Infarction
Leukemia
Loss of blood
Surgery/smoking
mature, segmented nucleus
segmented neutrophils
less mature neutrophils, have an unsegmented nucleus shaped like a C
band neutrophils
left shift
increase in immature cells, often from bacterial, inflammation, tissue damage
indicates a patient’s real risk of infection
ANC = WBC x (%neutrophils + bands)
absolute neutrophil count (ANC)
What’s a normal ANC ?
2500-8000