CC Flashcards

(41 cards)

1
Q

What are lipids primarily composed of?

A

C-H bonds

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2
Q

What is a primary function of lipids in living cells?

A

Energy storage

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3
Q

What type of bonds and terminal group do fatty acids have?

A

C-H bonds and -COOH

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4
Q

How are fatty acids classified when they are bound to albumin?

A

Unesterified

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5
Q

Which type of fatty acid contains no double bonds?

A

Saturated

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6
Q

How many fatty acids are attached to one molecule of glycerol in triglycerides?

A

3

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7
Q

What kind of lipid is cholesterol classified as?

A

Unsaturated steroidal alcohol

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8
Q

What is the primary role of chylomicrons?

A

Transport triglycerides after a meal

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9
Q

Which lipoprotein is known as ‘good cholesterol’?

A

HDL

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10
Q

In which lipoprotein is apoprotein B-100, along with some E, found on its surface?

A

IDL

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11
Q

Which enzyme is involved in the breakdown of triglycerides?

A

Lipase

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12
Q

What type of lipid metabolism disorder is associated with extremely elevated triglycerides due to enzyme deficiencies?

A

Hypertriglyceridemia

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13
Q

Which method is used for cholesterol measurement characterized by the Liebermann-Burchardt Reaction?

A

Bloors Method

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14
Q

What characterizes Familial Hypercholesterolemia?

A

Increased LDL cholesterol with normal intracellular cholesterol

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15
Q

Hypoalphalipoproteinemia is indicated by a decrease in which circulating lipoprotein?

A

HDL

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16
Q

Which disease is an extreme form of hypoalphalipoproteinemia characterized by the absence of HDL?

A

Tangier’s Disease

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17
Q

What is the primary function of chylomicrons in the body?

A

Transport dietary triglycerides

18
Q

Which lipoprotein is like a ‘cleanup crew’ gathering excess cholesterol?

A

High-density lipoproteins (HDLs)

19
Q

According to the notes, what causes cardiovascular disease when in excess?

20
Q

What is the primary role of cholesterol in lipoproteins?

A

Facilitating triglyceride transport

21
Q

Which fatty acid is most commonly found in dietary trans fats due to food processing?

22
Q

Triglycerides from plant sources are rich in which type of fatty acids?

A

Polyunsaturated fatty acids

23
Q

Which of the following is the most common phospholipid found in cell membranes?

A

Phosphatidylcholine

24
Q

What type of lipid molecule is characterized by having both hydrophobic and hydrophilic regions?

A

Amphipathic lipid

25
Where is cholesterol primarily synthesized in the body?
Cytosolic compartment
26
Which enzyme is the rate-limiting enzyme in cholesterol biosynthesis?
HMG-CoA reductase (HMHCR)
27
What type of bond attaches fatty acids to the glycerol backbone in triglycerides?
Ester bond
28
What is the primary adverse effect of trans fatty acids on lipoproteins?
Elevation of LDL and decrease in HDL
29
Which lipid is classified as a neutral lipid due to lack of charged or polar hydrophilic groups?
Triglyceride
30
What structural component allows apolipoproteins to bind lipids?
Amphipathic α helix
31
What is the main role of lipoproteins?
To deliver fuel to peripheral cells
32
Which apolipoprotein is the principal protein of LDL, VLDL, and chylomicrons?
Apo B
33
What apolipoprotein is a ligand for the LDL receptor?
Apo B100
34
Which lipoprotein particle contains Apo B48 and is known for its large size?
Chylomicrons
35
What happens to chylomicron triglycerides and cholesteryl esters once they enter the circulation?
They are hydrolyzed by lipases
36
Which lipoprotein is primarily produced by the liver and is rich in triglycerides?
VLDL
37
Which lipoprotein particle is primarily synthesized by both the liver and the intestine? HDL
HDL
38
Which lipoprotein particle can infiltrate into the extracellular space of vessel walls, leading to potential plaque formation?
LDL
39
What is the main lipid component of Lipoprotein X?
Phospholipids
40
What is the primary function of chylomicrons?
To deliver dietary lipids to hepatic and peripheral cells
41
Which lipoprotein particles reflect light and cause turbidity in fasting hyperlipidemic plasma specimens?
VLDL