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Flashcards in Cell Biology Deck (18):
1

Describe the phenomenon of "Sorting Out"

When cell were forced to lose their adhesion to each other, and were mixed together, they reformed their respective cell types and segregated.

2

What is the conclusion of the "Sorting Out" experiment?

Cell must have surface differences that differentiate their cell type.

3

What are cadherins, and what does the acronym mean?

Calcium dependent adherence proteins

4

Cadherins are ____ proteins. In the cytoplasm, they connect to ____ via alpha and beta proteins.

transmembrane, actin

5

Adherens junctions

Contain cadherins, and are useful for adhering cells together.

6

Gap Junctions

Little tubes that go between cells

7

Desmosomes

like weld spots that are used for structural stability

8

Tight Junctions

Tight selectively permeable chicken wire that separates the main cell body from e.g microvili

9

What is the ordering from out to inside of ECM to cytoskeleton?

Collagen to fibronectin to integrins to cytoskeleton microfilaments. The proteoglycans fill space.

10

Basal lamina

Where the cell rest on the ECM. Attached by specialized integrins and hemidesmosomes.

11

Three types of cytoskeleton polymers

Microtubules, microfilaments, intermediate filaments

12

Microtubules

Used for transport, and made from tubulin polymers

13

Microfilaments

made from actin polymers, thin

14

Intermediate Filaments

made from IF dimers.

15

Molecular Motors: Dyneins move toward:

negative end of Microtubules

16

Molecular Motors: Kinesins move toward:

positive end of microtubules

17

Thin crawling protrusions

filopodia

18

broad and flat crawling protrusions

lamellipodia