Cell cycle and cell division Flashcards

1
Q

what is the duration of a cell cycle of yeast ?

A

90 min

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2
Q

what is the duration of a cell cycle of a fibroblast cell ?

A

24 hrs

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3
Q

cell cycle is under genetic control of which enzymes ?

A
  1. cyclin
  2. CDK - cyclin dependent protein kinase / cell division kinase
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4
Q

in which stage the DNA replication takes place ?

A

S phase

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5
Q

what is the duration of cell cycle of Ecoli ?

A

20 min

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6
Q

what are the two phases of the cell cycle ?

A
  1. interphase
  2. m phase
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7
Q

interphase is also known as ?

A

prepratory/non dividing/resting phase

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8
Q

x% of time is required for interphase ?

A

95% = 23hrs

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9
Q

x% of time is required for m phase ?

A

5% = 1hr

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10
Q

interphase is divided into which three stages ?

A
  1. G1 phase
  2. S phase
  3. G2 phase
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11
Q

m phase is divided in which two stages ?

A
  1. karyokinesis
  2. cytokinesis
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12
Q

duration of G1 phase

A

11hrs

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13
Q

duration of s phase

A

8hrs

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14
Q

duration of G2 phase

A

4 hrs

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15
Q

karyokinesis of m phase is divided into which 4 stages ?

A
  1. prophase
  2. metaphase
  3. anaphase
  4. telophase
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16
Q

time interval between previous mitosis and initiation of DNA replication is called ?

A

G1 phase

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17
Q

in G1 phase cell is in which metabolic state ?

A

highly metabolically actives state.

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18
Q

synthesis of what takes place in G1 phase ?

A

RNA, Protein, ATP synthesis takes place

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19
Q

maximum growth in which cell organelles takes place in G1 phase ?

A

nucleus and cytoplasm

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20
Q

which cell organelles do not replicate in G1 phase ?

A

mitochondria and chloraplast

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21
Q

a point at the end of the G1 phase when crossed the cell is not able to enter into G1 phase again is called________ in mammals and _________ in yeast ?

A

restriction point in mammals
start point in yeast

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22
Q

DNA synthesis takes place in which phase ?

A

S phase

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23
Q

in animal cell which cell organelle duplicates in S phase ?

A

centriole

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24
Q

which protein gets synthesized in the S phase ?

A

Histone protein

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25
amount of content of DNA gets _______ in S phase
double
26
amount of chromosome _________ in s phase
remains same
27
shortest phase of interphase is
G2 phase
28
G2 phase is also called
cytoplasmic growth phase
29
what get synthesized in G2 phase ?
RNA, protein, ATP synthesis
30
duplication of which cell organelle takes place in G2 phase ?
mitochondria and chloroplast
31
which monomer protein forms in G2 phase ?
α , β - tubulin monomer protein
32
G0 phase is also known as
quiescent stage
33
G0 stage metabolically ________ but __________ for cell division
metabolically active but inactive for cell division
34
which cells do not show division ?
heart cells and most of the nerve cells
35
what is apoptosis ?
natural cell death program
36
unavaibility of _________ leads to G0 stage
mitogens
37
what is mitotic poison ?
they oppose mitosis
38
mitogens in plants are
auxin and cytokinin
39
actual cell division phase is
M phase
40
in animal cells mitosis usually takes place in which type of cell ?
diploid somatic cells ( non reproductive cells )
41
examples of haploid cells are
male drone species honey bees
42
in which haploid cell does mitosis takes place ?
marchantina
43
mitosis is also known as
equational division
44
which is the most dramatic phase of cell cycle ?
M phase
45
which is the first stage of karyokinesis of mitosis
prophase
46
which is the longest phase of karyokinesis ?
prophase
47
DNA molecules are not distinct but intertwined in which phase
G2 phase
48
prophase is marked by
initiation of condensation of chromosomal material
49
centriole begins to move towards the opposite poles in which phase ?
prophase
50
prophase is divide in two phases
early prophase and late prophase
51
chromosomes appear as long, thin, single stranded structure in which phase
early prophase
52
in early prophase nucleolus is attached to chromosome at ______________
nuclear organiser region
53
in early prophase chromatin undergo dehydration to form long, thin and coiled structure this process is called as
spiralization
54
in early prophase chromosome ends are indistinct and appear ball of wool called as
sprime stage
55
multi-protein complex innvolved condensation of chromosome in late prophase are
condensin cohesin
56
kinetochore protein gets mature in ___________prophase
late prophase
57
centriole reach to the opposite poles and start spindle formation in ___________prophase and start radiating out __________
late prophase microtubules
58
nuclear envelope, nucleolus, golgi complex, endoplasmic reticulum ___________ in late prophase
disappear
59
the two aster rays together with spindle fibers forms
mitotic apparatus
60
prometaphase is charctersised by ______________
complete disintegration of nuclear envelope and nucleolus
61
aster formation is completed and mitotic spindle is attached to kinetochore in which transition phase ?
transition to metaphase / prometaphase
62
the start of metaphase is marked by
complete disintegration of the nuclear envelope
63
best stage to study the morphology of the chromosome is
metaphase
64
kinetochore acts as a __________ for the spindle fibers
attachment site
65
what is metakinesis ?
the tightening of chromosomal fibers brings all the chromosomes at he equator of the cell in metaphase it is also known as compression
66
metaphase is characterised by
allignement of all the chromosomes at the equator of the cell