Cell Cycle, etc Flashcards
What is the cell theory?
- All living things are made of one or more cells
- Cell is the basic unit of life
- New cells arise from existing cells
Purpose of cell cycle
- New cells needed
- Replace dead cells
- Regular cell death
- Asexual reproduction
Process of Binary fission
- Bidirectional replication of DNA
- DNA moves to poles
- Cell elongates and cleavage furrow forms
- Cytokenisis - cell divides.
Compare Binary fission to Mitosis
- Only 20 mins
- Much faster
- Asexual reproduction
- Single strand DNA splits into 2
- Undefined processes.
What is Chromatin made of
- Tightly wounded histones and proteins.
Characteristic of homologous chromosomes
- Same gene located on same loci of each pair.
Which genders DNA determines sex of offspring?
MALE
How many genes does X and Y chromosomes carry?
X = up to 1500
Y = up to 300
What is the default gender?
Female
Define Karyotype?
Collection of chromosomes in an inidivudal
Characteristics of chromosome pairs
- Different size to others
- Different no. genes to other pairs
Define Locus
Location of individual genes
cell cycle checkpoint??
G1- PREPARATION FOR DNA REPLICATION/ grows
Sā DNA REPLICATION (error= apoptosis)
G2- PREPARW FOR MITOSIS
M- Check if chromosomes r allighnednproperly in metaphase (error = apoptosis)
G0- if cell is under stress/ delay , pause and apoptosis or improve
Dna replicarion
- Double helix unzips
- Polymerase adds nucleotides to strand.
Centrosomw
Where microtubules are produced. Has two centrioles made of 9 ringed microttubules.
Prophase
Chromosomes condense
Nuclear envelope disappears
Centrosomes move to opposire poles
Apoptosis
Programmed cell death
Undegoes during wnd of cell life
Dysfunctional or damaged
Lipid based hormones
LIPID BASED HORMONES SUCH AS STEROID HORNONES TRAVEL THEOUGH BLOOD INTO CARRIER PROTEIN
Protein based hormone
Such as amine hormone or peptide hornone travel freely in blood but cant pass phospholipid bikayer unless receptor
Stages og apoptosis
Caspaces are triggered
Divide (cleave) Intracellular materials are digested
Cell shrink - nucleus and organelles
Blebing - cytoskeleton dies, cell weakens and splits into small vesicles called apoptotic bodies
Phagocytosis - apoptotic bodies get engulfed snd digested by phagocytes
Extrinsic pathway
Signalling molecules attack to desth receptors on plasma membrane
Procadpaces activated
Cell undergoes apoptosis
Reason for extrisnicnpathway
- no longer needed
- replaced by new cell
- nonfunctional