cell division Flashcards

1
Q

3 reasons cell replication occurs

A
  1. replacing dead cells (repair 2. growth and maitenance
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2
Q

how do prokaryotes replicate

A

via binary fission

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3
Q

what is prkaryotic binary fission

A

each cell becomes 2 identical copies, this is asexual reproduction

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4
Q

3 main categories of the cell cycle

A

interphase, mitosis and cytokinesis

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5
Q

what are the phases in mitosis

A

prophase, metaphase, anaphase, telophase (cytokinesis)

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6
Q

what are the three phases in the interphase

A

gap 1, synthesis (gap 0), gap 2

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7
Q

what happens in gap 1 (interphase)

A

period of cell growth, normal metabolism, duplication of organelles

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8
Q

what happens during the synthesis stage (interphase)

A

near the end of interphase, chromosomes duplicate to form two chromtids that are held together at the centromere

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9
Q

what happens during interphase gap 2

A

cell grows and prepares itself for mitosis, involves increasing the volume of the cytosol and synthesising proteins in preparation for mitosis

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10
Q

what happens during prophase

A

chromosomes coil/condense and become visible, centrioles move apart to opposite poles and spindles begin to form, late prophase the nuclear membrane breaks down

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11
Q

what happens during metaphase

A

chromosomes appear as two sister chromatids joined at the centromere, chromosomes line up at the equator, microtubules of spindle attach to centromeres

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12
Q

what happens during anaphase

A

microtubules contract, pulling centromeres and chromotids apart and moving them towards centrioles at opposite poles. chromotids are now considered new chromosomes

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13
Q

what happens during telophase

A

spindle fibers breakdown, nuclear envelope forms around each group of chromosomes and chromosomes unravel to become invisible again

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14
Q

what happens during cytokinesis

A

the plasma membrane pinches in to seperate the two nuclei, cytoplasm is divided to form two new daughter cells

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15
Q

what is cell cycle regulation

A

if errors are detected at checkpoints, the cell wither repairs itself or will undergo programmed cell death - apoptosis

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16
Q

what does the g1 checkpoint verify

A

grown to correct size, synthesised enough protein for DNA replication, if DNA has been damaged during previous mitosiss and cell growth

17
Q

what does the g2 checkpoint verify

A

dna has replicated properly during the s phase, cell has enough resources for mitosis

18
Q

what does the metaphase checkpoint verify

A

formation of spindle fibers, choromsomes are lined up correctly

19
Q

where are the three checkpoints

A

g1 g2 and metaphase

20
Q

what can cause checkpoints to malfunction

A

mutagens/dna mutations or indivdual genetics

21
Q

what is apoptosis

A

programmed cell death

22
Q

what are the two pathways of apoptosis

A

mitochondrial and death receptor

23
Q

is apoptosis the only way cells can die

A

no e.g necrosis, damage by oathogens, physical injury

24
Q

what are capases

A

enzymes that digest cell contents

25
Q

what are the stages of apoptosis

A
  1. capases are activated in the cell 3. cells shrinks - blebs and nucleus condenses 4. partition of cytoplasm and nucleus into apoptotic bodies which are engulfed by pphagocytosis