Cell Isolation Flashcards by Alan O'Mahony | Brainscape

Q

Haemopoietic stem and progenitor cells (CD34+)

A

Capable of repopulating the entire immune system
Responsible for production of RBCs
4916 clinical trials worldwide

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Q

Mesenchymal stem cells (MSCs)

A

Adhere to plastic
Express CD73, CD90 & CD105
Lack expression of CD14/CD11b, CD79a/CD19, CD34 & HLA-DR
Osteogenic, adipogenic & chondrogenic differentiation potential

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Q

Mobilised peripheral blood stem cells associated with higher risk of…

A

Both acute/chronic GVHD

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Q

Umbilical cord is a rich source of…

A

HSPCs and MSCs
Blood contains 0.34% CD34+ cells
Harvesting also a painless and non-invasive procedure
Considered medical waste

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