cell signalling and cell membrane Flashcards

1
Q

balls like structures of phospholipids

A

micelles

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2
Q

sheet like structures of phospholipids

A

bilayers

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3
Q

fluidity in fluid mosaic model

A

both phospholipids and proteins can move

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4
Q

mosaic in fluid mosaic model

A

pattern produced by the scattered proteins molecules when cell membrane is viewed from above

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5
Q

what to double c-c bonds to do fluidity

A

unsaturated tails make the membrane more fluid as fatty acid tails are bent and fit together more loosely

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6
Q

what happens to fluidity as temp decreases

A

it decreases as there is less ke and phospholipids move less and pack together

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7
Q

cholesterol

A

acts as fluidity buffer, stops pl packing together when low temps
hydrophobic regions help prevent ions and polar molecules form passing through

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8
Q

5 things the gp+gl+pr can be for

A

receptor molecules
cell to cell recognition
transport proteins
enzymes
cytoskeleton

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9
Q

channel proteins

A

water filled pores
allow charged substances(ion) to diffuse and water
gated
only down conc gradient

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10
Q

carrier proteins

A

flip between 2 shapes
transport up and down conc gradient

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11
Q

cell signalling

A

molecular mechanisms by which cells detect and respond to external stimuli including communication between cells

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12
Q

step of cell signalling

A
  1. stimulus causes cell to secret a ligand
    2.ligand is transported to target cell
    3.ligand binds to cell surface receptor on the target cell
  2. transduction- ligand causes change of shape of receptor
    5.receptor spans membrane so message is passed to inside of cell
    6.response
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13
Q

autocrine signalling

A

receptors on releasing cells

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14
Q

paracrine signalling

A

receptors on adjacent cell

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15
Q

endocrine signalling

A

signals have to travel through blood

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16
Q

ligand

A

a biological molecules which binds to another molecule like a cell surface membrane receptor during cell signalling

17
Q

transduction

A

process of converting a signal from one method of transmission to another

18
Q

4 factors affecting diffusion

A

nature of molecules
surface area
temp
steepness of conc gradient

19
Q

what to channel p carry

20
Q

aquaporins

A

type of channel protein for water as when water diffuses normally it is slow

21
Q

what to carrier p carry

A

glucose, amino acids, nucleotides, sugar

22
Q

what are channel p

A

hydrophilic pores in cell membrane
only down conc gradient

23
Q

what are carrier p

A

integral proteins up and down conc gradient

24
Q

water potential

A

tendency of water to move from one place to another

25
wp depends on
conc of sol pressure applied
26
endocytosis
the bulk movement of liquids or solids into a cell by the unfolding cell surface membrane to form vesicles containing the substance requires app
27
exocytosis
the bulk movement of liquids or solids out of a cell by the fusion of vesicles containing the substance with the cell surface membrane active process requires atp
28
phagocytosis
bulk uptake of solid material. phagocytes specialise in this
29
bulk uptake of liquid
pinocytosis/micropinicytosis
30
3 stages of cell signalling
reception transduction and response
31
what is transduction
the receptor changes shape triggering the signal to be passed along multistep pathway. the signal is converted to a message that can be passed on
32
signalling amplification
many secondary messengers in response to one activated receptor (signalling cascade)