Cells Flashcards

(75 cards)

1
Q

Why do cells change?

A

Grow and differentiate jobs

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2
Q

Is cell changing normal?

A

Minor alterations are normal

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3
Q

Do abnormal changes always mean tumors or cancer?

A

No, abnormal changes doesn’t necessarily mean permanent cell/tissue damage, tumors or cancer

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4
Q

Is it okay to have atypical cells?

A

Yes!

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5
Q

Is it okay to have abnormal cells?

A

No, because they could be cancerous

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6
Q

How do cells change?

A

Size, number, type

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7
Q

What are changes in size?

A

Atropy and Hypertrophy

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8
Q

Atrophy

A

Decrease in cell size

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9
Q

Hypertrophy

A

increase in cell size

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10
Q

What causes atrophy?

A

Decreased use, decreased blood supply, decreased nutrition, and in tissues and organs, it can cause cell shrinkage or death

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11
Q

What causes hypertrophy?

A

Cells adapt to their environment such as inflattion and hormones (like bloating on your period), overuse of an organ or tissues, can also be normal physiological response

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12
Q

What causes cardiac hypertrophy

A

Mycardial fibers increase in size due to increased workload

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13
Q

Change in numbers

A

Hyperplasia, dysplasia, anaplasia

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14
Q

Hyperplasia

A

increase in number of cells

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15
Q

What causes Hyperplasia?

A

Increase in cell division

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16
Q

Dysplasia

A

Increase in number of atypical cells

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17
Q

Atypical cells with Dysplasia

A

abnormal cell size, shape or organization

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18
Q

What type of cells does dysplasia occur in?

A

Mature cells only

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19
Q

Anaplasia

A

increase in number of abnormal cells (cancer)

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20
Q

What happens to cells in anaplasia

A

Cells lose unique characteristics that define them as certain types of tissue

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21
Q

Change in cell type

A

Metaplasia and Neoplasia

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22
Q

Metaplasia

A

Change one type of mature cell type to a different mature cell type

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23
Q

Neoplasia

A

“New growth” tumor

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24
Q

What is the exact definition of Neoplasia

A

New growth

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25
Neoplasm means
tumor/cancer
26
What is cancer
uncontrolled proliferation of cells that express varying degrees of fidelity to their precursors
27
What are the two types of cancer
Benign and Malignant
28
Benign Tumors
Cells grow as a compact mass and remain at their site of origin
29
Malignant
Growth of cells is uncontrolled and cells can spread into surrounding tissues and spread to distant sites
30
Cell injury
cell is exposed to an injurious agent or stress, a sequence of events follows
31
Is cell injury reversable?
Up to a certain point
32
Cell death
If stimulus persists or is severe enough from the beginning
33
Can cell injury lead to cell death?
Yes, if a cell suffers irreversable cell injury
34
What are the two types of cell death?
Apoptis and Necrosis
35
When does apoptis occur?
occurs when a cell dies throuh programmed cell death
36
What does Apoptis do?
Eliminates unwanted cells when development is abnormal
37
When does necrosis occur?
occurs after ischemia?chemical inury
38
What is ischemia?
Deficit of exygen
39
Is necrosis always pathological?
Yes!
40
What are the types of necrosis?
Liquefactive, coagulative, fat, caseous, and gangrenous necrosis
41
Liquefactive necrosis
Dead cells liquify
42
What often causes liquefactive necrosis?
bacterial infections and sometimes fungal
43
What happens to the tissue during liquefactive necrosis?
Tissue turns into a liquid viscous mass
44
Coagulative Necrosis
Occurs when cell proteins are altered
45
What is the process of coagulation?
Cooking an egg
46
Fat necrosis
Enzymes break down fatty tissue into fatty acids
47
What does fatty necrosis look like?
Chalky white areas
48
Caesos Necrosis
Type of coagulative necrosis, seen in tuberculosis infection
49
What does Caesos Necrosis look like?
Type of coagulative necrosis, seen in tuberculosis infection
50
What does caseous necrosis look like?
Yellowish "sheesy" appearance
51
Gangrenous Necrosis
Limb has lost blood supply and has undergon coagulation necrosis
52
What if gangrenous necrosis is wet?
Coagulation and liquefactuve necrosis
53
What is water?
Medium in which reactions/processes take place, transportation system of the body
54
How much of the adult body weight is water?
60%
55
How does age affect the total body water?
Infants have about 70% TBW (TBW decreases in older adults
56
How does sex affect the TBW
females typically have higher fat
57
How does fat affect the TBW
fat means a lower proportion of water
58
Individuals with ___ are more likely to be adversely affected by any fluid or electrolyte imbalance
Less fluid reserve
59
What are the fluid compartments?
Intracellular fluids and extracellular fluids
60
Where are intracellular fluids found
Fluid within the cell
61
Extracellular fluids are found
outside of the cell
62
Why does balance in these compartments matter?
Homeostasis
63
Intracellular fluids are
inside cell, 2/3 of fluid volume
64
Extracellular fluids are
Intravascular fluids (1/4 of fluid) and intestinal fluid (3/4)
65
What are other transcellular fluids?
Cerebrospinal fluid (CSF), various secretion, lymphatic fluid, synovial and serous cavities
66
What is the movement of water?
Amount entering should equal amount leaving
67
What do the cell membranes do to keep homeostasis?
Cell membranes are selectively permeable, so they maintain appropriate concentrations of substances by active and passive processes
68
What separates the intra vascular fluid and intracellular fluid?
The cell membrane!
69
Is osmosis passive or active?
Passive!
70
How do fluids circulate through the body?
FIlitration and osmosis
71
Filitration
movement of water and solutes from high pressure to low pressure
72
Osmosis
movements of water from high water to low water concentration or low solute to high solute concentration
73
How does water move between IVF and ISF compartments?
Hydrostatic Pressure and Osmotic pressure
74
Hydrostatic Pressure
tends to push watter and solutes out of IVF and into ISF
75
Osmotic Pressure
tends to push water and solutes into to IVF and out of ISF