Cells and Tissues of the Immune System Flashcards Preview

FDN3 By Nathan and Minnie > Cells and Tissues of the Immune System > Flashcards

Flashcards in Cells and Tissues of the Immune System Deck (156)
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1

What are primary lymphoid tissues?

Primary lymphoid tissues are where white blood cells originate and develop.

Bone marrow and thymus

2

What tissues comprise primary lymphoid tissues?

Bone marrow and thymus

3

What are secondary lymphoid tissues?

Secondary lymphoid tissues are where white blood cells migrate to interact and generate an effective, adaptive immune response

Lymph nodes, tonsils, spleen, lymphoid tissues (MALT, GALT, BALT)

4

What tissues comprise secondary lymphoid tissues?

Lymph nodes, tonsils, spleen, and lymphoid

5

Where do all WBCs originate?

Bone marrow

6

What does the common stem cell give rise to?

Lymphoid stem cells and myeloid stem cells

7

Which cells are derived from myeloid cells?

  • Neutrophils
  • Eosinophils
  • Basophils/mast cells
  • Monocytes/macrophages
  • Other antigen-presenting cells

8

Which cells are derived from lymphoid cells?

  • B-Cells
  • T-Cells
  • Natural Killer Cells

9

Where do all myeloid-derived cells mature?

Bone marrow

10

What does the lymphatic system consist of?

  • Lymph veseels
  • Tissues and organs w/ high density of lymphocytes
    • Lymph nodules
    • Lymph nodes
    • Thymus gland
    • Mucosa-associated lymphatic tissue
    • Bone marrow

11

What kind of cell is this?

Neutrophil; Multi-lobed nucleus

12

What kind of cell is this?

Eosinophil;

Bi-lobed cells with bright pink cytoplasmic granules

13

What kind of cell is this?

Basophil;

Deep blue, dark cytoplasmic granules

14

What is MALT called when it is in the gut?

Gut-associated lymphatic tissue (GALT)

15

What is MALT called when it is in the airway?

Bronchus-associated lymphatic tissue (BALT)

16

What kind of cell is this?

Mast Cell;

Deep blue dark cytoplasmic granules

17

What are antigens?

Substances, tissues, or infectious organisms foreign to the body

18

What kind of cell is this?

Where are you likely to find it?

Monocyte; kidney shaped nucleus, lilac cytoplasm

Found in peripheral blood

19

What are the functions of supporting cells?

Regulate immune response and play roles in presenting antigen to lymphocytes

20

What does the stroma of lymphatic nodules, nodes, and spleed consist of?

Reticular fibers (small diameter collagen fibers w/ high sugar content)

 

Produced by reticular cells

21

What does the stroma of the thymus consist of?

Branching interconnecting epithelioreticular cells

 

From third branchial pouches

22

Which cell types are surveillance cells?

  • Macrophages
  • Langerhans cells (epidermis)
  • M cells (intestinal epithelium overlying lymph nodules)
  • Dendritic cells (lymphatic tissues)

23

What kind of cell is this?

Where is it found?

Macrophage;

Reside in tissues

24

Describe the path that long-lived circulating lymphocytes move in

  1. Leave blood venules to enter lymphatic organs and tissues for immune surveillance
  2. Re-enter circulation to go to other lymphatic tissues
  3. Pass through walls of vasculature in high endothelial venules in lymphatic tissues and organs (postcapillary)

25

What kind of cell is this?

Could be a B cell or a T cell (the picture in Dr. Wolniak's ppt is the same for both)

Identification may depend on location

- B Cells mature in the Bone marrow

-T Cells mature in the Thymus gland

26

What kind of cell is this?

Plasma Cell;

Fried egg appearance, "clock face" chromatin pattern in nucleus

27

What is unique about high endothelial venules in lymphatic tissues and organs?

The endothelium is cuboidal instead of simple squamous

28

Describe the path that short-lived circulating lymphocytes move in

One-way migration out of blood vessels to populate connective tissue of GALT and mucosa of airway

29

What kind of cell is this?

Natural Killer Cell;

Granules produce cytotoxins to kill other molecules

30

Where are T lymphocytes mainly found?

Diffuse lymphatic tissue of lymphatic organs or loose connective tissue of GI, respiratory, urinary tracts