Cells of the NS Flashcards
What are the role of radial glial cells in adults?
Migrate out of ventricular zone to turn into astrocytes. Generate neurons, and continue to generate intermediate progenitor cells.
What are the 3 major parts of a neuron?
Soma (cell body), dendrites, axons.
What are dendrites?
allow connections, can receive multiple connections from other neurons, branching occurs in early stages.
What are axons?
Forms contact with other cells, contains bouton (end terminal for synapse). May contain myelin sheath.
What are the 3 types of synapses?
With other neurons, neuromuscular junctions, neuroglandular synapse.
What are the 3 types of connection with other neurons?
Axodendritic, axosomatic, axoaxonic.
What are the types of glial cells found in CNS?
Astrocytes, microglia, oligodendrocytes, radial glial.
Where are radial glial cells found after neurogenesis?
Cornea, cerebellum, small deposits in cortex.
What are astrocytes?
Most abundant, for structural, metabolic support to axons, provide nutrients, involved in the BBB, responsible for glial scars
What are Glial Scars?
Barrier and maintain physical, chemical integrity of CNS, provide barrier from lesion site, ensure no transmission. Prevents neuronal re-growth.
What are microglia?
Small cells stimulated by antigen, process harmful bacteria during immune response.
What are oligodendrocytes?
Arms extend from cell body forming myelin. Key component to conduction of action potential. Also present in Optic Nerve.
What is MS?
Multiple sclerosis, higher prevalence in women, autoimmune disease, damage to myelin sheath replaced by scar tissues and plaque.
What are the 4 types of MS?
Relapsing remitting, Secondary progressive, primary progressive, progressive relapsing.
What are the symptoms of MS?
https://mssociety.ca/about-ms/symptoms
