Flashcards in CellSig1 - 10 Deck (10):
Define signal transduction
Process by which EC signalling molevules cause changes in target cells
7 types of signal
Proteins, small peptides, amino acids, nucleotides, steroids, fatty acid derivatives, dissolved gases
Define paracrine signalling
Define autocrine signalling
Signalling to itself, or same tissue
What kind of molecules can signal by gap junction signalling?
Small molecules such as cAMP and Ca2+
What are gap junctions made from?
6 connexins in each membrane (2 connexons of 6 connexins)
Describe a gap junction with mixed connexins
Describe a gap junciton with all the same connexins
What characterises endocrine signalling?
Slow, low concentrations, high affinity receptors