Cerebellum Flashcards

(90 cards)

1
Q

Cerebellum unconsciously influences the

A

smooth contraction of voluntary
muscles and carefully coordinates their actions, together with the
relaxation of their antagonists

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2
Q

Each cerebellar hemisphere controls

A

muscular movements on the
same side of the body and the cerebellum has no direct
pathway to the lower motor neurons but exerts its control via the
cerebral cortex and the brainstem

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3
Q

control of posture and voluntary movements

A

Cerebellum

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4
Q

Cerebellum location

A

Posterior Cranial Fossa

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5
Q

Largest part of the Hindbrain

A

Cerebellum

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6
Q

Cerebellum lies posterior to the

A

fourth ventricle, the pons,
and the medulla oblongata

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7
Q

Three main lobes of the cerebellum

A

the anterior lobe,
the middle lobe, and the flocculonodular lobe

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8
Q

seen on the superior surface of the
cerebellum

A

Anterior lobe

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9
Q

Anterior lobe is separated to the middle lobe by a wide V-shaped fissure

A

primary fissure

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10
Q

Associated lobule to the ant. lobe

A

Quadrangular Ala of Central lobule

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11
Q

largest part of the cerebellum

A

Middle lobe

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12
Q

middle lobe is situated between the

A

primary and uvulonodular fissures

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13
Q

Associated lobule of the middle lobe

A

Simplex
Superior semilunar
Inferior semilunar
Biventral
Tonsil

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14
Q

lies posterior and inferior to, separated bu

A

anterior lobe, primary fissure tonsil

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15
Q

Cerebellar tonsils lie just lateral to the
medulla and, if displaced by pressure, can compress the medulla,
causingg death

A

tonsillar herniation

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16
Q

flocculonodular lobe is situated posterior to the

A

uvulonodular
fissure

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17
Q

Associated lobule of the flocculonodular lobe

A

Flocculus nodule of the vermis

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18
Q

Flocculus is separated from the middle lobe
by

A

posterolateral fissure

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19
Q

Significance of the flocculonodular lobe

A

involved in balance by communicating
with vestibular system

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20
Q

atrophic in alcoholics

A

Anterior lobe

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21
Q

composed of an outer covering of gray matter called the __
and__

A

cortex, inner white matter

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22
Q

Embedded in the white matter of each hemisphere are three
masses of gray matter forming the

A

intracerebellar nuclei

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23
Q

Each fold or folium contains a core of white matter covered
superficially by gray matter

A

Cerebellar Cortex

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24
Q

3 layers of gray matter

A

an external layer, the molecular layer
a middle layer, the Purkinje cell layer
an internal layer, the granular layer

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25
molecular layer contains two types of neurons
outer stellate cell and the inner basket cell
26
These neurons are scattered among __ and numerous thin axons that run parallel to the long axis of the folia. __ are found between these structures
dendritic arborizations, Neuroglial cells
27
flask shaped and are arranged in a single layer.
Purkinje cells are large Golgi type I
28
At the base of the Purkinje cell, the axon arises and passes through the ___ to enter the white matter
granular layer
29
Collateral branches of the Purkinje axon make synaptic contacts with the dendrites of __of the granular layer in the same area or in distant folia.
basket and stellate cells
30
Granular layer is packed with small cells with densely staining nuclei and scanty cytoplasm. Each cell gives rise to __ dendrites, which make claw-like endings and have synaptic contact with __
4/5, mossy fiber input
31
Granular layer The axon of each granule cell passes into the __ layer, where it bifurcates at a __junction , the branches running parallel to the long axis of the __
molecular layer, T , cerebellar folium
32
run at right angles to the dendritic processes of the Purkinje cells.
parallel fibers
33
influences the movements of the long axis of the body , namely, the neck, the shoulders, the thorax, the abdomen, and the hips
Vermis
34
to control the muscles of the distal parts of the limbs, especially the hands and feet.
intermediate zone of the cerebellar hemisphere
35
Immediately lateral to the vermis is a so-called
intermediate zone of the cerebellar hemisphere
36
concerned with the planning of sequential movements of the entire body and is involved with the conscious assessment of movement errors.
lateral zone of each cerebellar hemisphere
37
Intracerebellar Nuclei
- Dentate, Globus & Emboliform, Fastigial
38
: largest, lateral-most deep nucleus
Dentate Nucleus
39
Dentate Nucleus Input & Output
Input: Lateral Hemisphere Output: SCP
40
Globose Nuclei & Emboliform nucleus collectively
Interposed nucleus
41
Interposed Nucleus Input & Output
Input: Paravermin Output: SCP
42
medial-most deep nucleus
Fastigial Nucleus
43
Fastigial Nucleus Input & Output
Input: Vermis Output: juxtarestiform body of the inferior cerebellar peduncles
44
closely resembles the trunk and branches of a tree and thus is termed
arbor vitae
45
amount of white matter in each cerebellar hemisphere. The white matter is made up of three groups of fibers:
intrinsic, afferent, efferent
46
do not leave the cerebellum but connect different regions of the organ. Some interconnect folia of the cerebellar cortex and vermis on the same side; others connect the two cerebellar hemispheres together
Intrinsic fibers
47
form the greater part of the white matter and proceed to the cerebellar cortex. They enter the cerebellum mainly through the inferior and middle cerebellar peduncles
Afferent fibers
48
constitute the output of the cerebellum and commence as the axons of the Purkinje cells of the cerebellar cortex
The efferent fibers
49
two main lines of input to the cortex and are excitatory to the Purkinje cells
climbing and the mossy fibers
50
terminal fibers of the olivocerebellar tracts
climbing fibers
51
terminal fibers of all other cerebellar afferent tracts.
mossy fibers
52
The deep cerebellar nuclei receive afferent nervous information from two sources:
the inhibitory axons from the Purkinje cells of the overlying cortex the excitatory axons that are branches of the afferent climbing and mossy fibers that are passing to the overlying cortex.
53
the excitatory climbing and mossy afferent fibers use
Gamma-aminobutyric acid (GABA)
54
other afferent fibers entering the cortex liberate
norepinephrine and serotonin
55
superior cerebellar peduncles connect the cerebellum to
midbrain
56
middle cerebellar peduncles connect the cerebellum to the
pons
57
the inferior cerebellar peduncles connect the cerebellum to the
medulla oblongata
58
arise from nerve cells in the frontal, parietal, temporal, and occipital lobes of the cerebral cortex and descend through the corona radiata and internal capsule and terminate on the pontine nuclei
corticopontine fiber
59
The pontine nuclei give rise to the
transverse fibers of the pons cross the midline and enter the opposite cerebellar hemisphere as the middle cerebellar peduncle
60
arise from nerve cells in the frontal, parietal, temporal, and occipital lobes of the cerebral cortex and descend through the corona radiata and internal capsule to terminate bilaterally on the inferior olivary nuclei
Cerebro-olivocerebellar pathway
61
Cerebro-olivocerebellar pathway give rise to fibers that cross the midline and enter the opposite
cerebellar hemisphere through the inferior cerebellar peduncle. These fibers terminate as the climbing fibers in the cerebellar cortex
62
arise from nerve cells from many areas of the cerebral cortex, particularly the sensorimotor areas.
Cerebroreticulocerebellar Pathway
63
They descend to terminate in the reticular formation on the same side and on the opposite side in the pons and medulla
Cerebroreticulocerebellar Pathway
64
This connection between the cerebrum and the cerebellum is important in the control of voluntary movement
Cerebroreticulocerebellar Pathway
65
anterior spinocerebellar tract
enter: PRG> Nucleus dorsalis of Clarke @ base of PGH Cross opp side in contralat white column Enter cerebellum via SCP Terminate as mossy fibers upper and lower limbs.
66
posterior spinocerebellar tract
Posterolat of lat white column ascend to medulla oblongata Enter in ICP Terminate as mossy fibers trunk and lower limbs
67
cuneocerebellar tract
terminate as mossy fibers in the cerebellar cortex. Collateral branches that end in the deep cerebellar nuclei are also given off upper limb and upper part of the thorax
68
The vestibular nerve sends many afferent fibers directly to the cerebellum through the
inferior cerebellar peduncle on the same side
69
receives information from the inner ear concerning motion from the semicircular canals and position relative to gravity from the utricle and saccule
Cerebellar Afferent Fibers From the Vestibular Nerve
70
vestibular afferent fibers pass
first to the vestibular nuclei in the brainstem, where they synapse and are relayed to the cerebellum All the afferent fibers from the inner ear terminate as mossy fibers in the flocculonodular lobe of the cerebellum.
71
Axons of neurons in the globose and emboliform nuclei travel through the
superior cerebellar peduncle
72
the globose and emboliform nuclei influence
motor activity on the same side of the body.
73
Axons of neurons in the dentate nucleus travel through the superior cerebellar peduncle and cross the midline to the opposite side in the decussation of the
superior cerebellar peduncle.
74
dentate nucleus can influence
motor activity by acting on the motor neurons of the opposite cerebral cortex; impulses from the motor cortex are transmitted to spinal segmental levels through the corticospinal trac
75
the dentate nucleus is able to
coordinate muscle activity on the same side of the body
76
The axons of neurons in the fastigial nucleus travel through the
inferior cerebellar peduncle and end by projecting on the neurons of the lateral vestibular nucleus on both sides
77
The fastigial nucleus exerts a facilitatory influence mainly on the
ipsilateral extensor muscle tone
78
The axons of neurons in the fastigial nucleus travel through the
inferior cerebellar peduncle
79
Fastigial Reticular Pathway influence
spinal segmental motor activity through the reticulospinal tract
80
produce sudden, severe symptoms and signs, patients can recover completely from large cerebellar injuries. other CNS areas can compensate for loss of cerebellar function
Acute lesions
81
such as slowly enlarging tumors, produce symptoms and signs that are much less severe than those of acute lesions. The reason for this may be that other CNS areas have time to compensate for loss of cerebellar function
Chronic lesions,
82
- muscles lose resilience to palpation. There is diminished resistance to passive movements of joints. Shaking the limb produces excessive movements at the terminal joints. The condition is attributable to loss of cerebellar influence on the simple stretch reflex
Hypotonia
83
Postural Changes and Alteration of Gait
head is often rotated and flexed, and the shoulder on the side of the lesion is lower than on the normal side. The patient assumes a wide base when he or she stands and is often stiff legged to compensate for loss of muscle tone. When the individual walks, he or she lurches and staggers toward the affected side
84
Tremor occurs when fine movements, such as buttoning clothes, writing, and shaving, are attempted. Muscle groups fail to work harmoniously, and there is decomposition of movement
Ataxia/Disturbances in Voluntary movement
85
is the inability to perform alternating movements regularly and rapidly
Dysdiadochokinesia
86
essentially an ataxia of the ocular muscles, is a rhythmical oscillation of the eyes
Nystagmus,
87
cerebellar disease because of ataxia of the muscles of the larynx
Dysarthria
88
The most common cause of vermis syndrome is a__ of the vermis in children. Involvement of the flocculonodular lobe results in signs and symptoms related to the vestibular system. There is a tendency to fall forward or backward. There is difficulty in holding the head steady and in an upright position
Vermis Syndrome, medulloblastoma
89
This rhythmic oscillation of the eyes may be of the same rate in both directions
pendular nystagmus
90