Cervical Cancer Flashcards

(32 cards)

1
Q

Screening has told us that most cases of such invasive cervical cancer, are in women who have never what?

A

Been previously screened or been HPV vaccinated.

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2
Q

Peak incidence age for cervical cancer

A

40’s, median is 47

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3
Q

Explain the screening program for pap testing

A

We start from age 21, from 21-65 a simple Pap test every 3 years, from 30 onwards, a pap and HPV testing. From 65 onwards, we stop if no history of dysplasia and 3 negative consequent tests

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4
Q

Micro invasive carcinoma definition?

A

Invasive cancer less than 5mm of invasion

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5
Q

Micro invasive carcinoma is classified as IA1 and IA2, explain both

A

1 is less than 3mm invasion, 2 is more than 3mm and less than 5.

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6
Q

Apart from the usual smears and colposcopies, what is the definitive diagnosis method of micro invasive carcinoma?

A

Cervical conization (a cone shaped sample is removed and analyzed)

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7
Q

Treatment for Stage IA1 micro invasive carcinoma

A

Total hysterectomy is standard. Therapeutic conization IF fertility is desired

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8
Q

Standard treatment for Stage IA2 Micro invasive carcinoma?

A

Modified radical hysterectomy

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9
Q

What is the fertility sparing option for stage IA2 micro invasive carcinoma?

A

Radical Trachelectomy

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10
Q

Cauliflower carcinoma location

A

Ectocervical

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11
Q

Nodular carcinoma location?

A

Endocervical

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12
Q

Describe an Ulcerative carcinoma

A

Raised everted edge, with a necrotic floor

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13
Q

The earliest and most important mode of spread?

A

Direct invasion

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14
Q

What’s the most important means of distal spread for carcinoma?

A

The lymphatic drainage system

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15
Q

The most common and obvious signs of cervical carcinoma?

A

Vaginal discharge is the earliest, and obviously contact bleeding during sex

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16
Q

In advanced stages, what signs can we look out for

A

Pelvic side wall involvement, a TRIAD of Flank pain, sciatic pain, and leg swelling.

17
Q

Bleeding on touch is the commonest for which type of carcinoma

18
Q

Explain IB1 classification

A

Invasive carcinoma bigger than 5cm but smaller than 2 cm in greatest dimension

19
Q

Explain IB2 classification

A

Invasive carcinoma smaller than 4cm in greatest dimension

20
Q

Explain IB3 classification

A

Invasive carcinoma bigger than 4cm in greatest dimension

21
Q

Explain stage 2 FIGO classification

A

Carcinoma invades beyond the uterus, but not extended into the pelvic wall or lower 3rd of the vagina

22
Q

Explain stage 3 FIGO classification

A

Carcinoma invades lower 3rd of the vagina.

23
Q

Stage 3A?

A

No extension into pelvic wall involvement

24
Q

Stage 3B?

A

Extension into pelvic wall

25
Stage 3C?
Extension into lymph nodes
26
Stage 4A?
Spread to adjacent organs
27
Stage 4B?
Spread to distant organs.
28
Stages of cervical cancer that are operable?
IA1 till 2A
29
After stage 2A, what is treatment?
Radiotherapy
30
What is the treatment for stage 1B till 2A?
Wertheim’s hysterectomy + radiotherapy
31
A 60-year-old with stage IVA cervical cancer (bladder invasion) develops ureteral obstruction. What is the best palliative intervention?
Nephrostomy tubes
32
Which lymph node group is the first echelon for cervical cancer metastasis?
Obturator