Ch 15B (pt.1): TA Review Flashcards

1
Q

What are the types of feedback regulation?

A

Positive feedback
Negative feedback

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2
Q

What is positive feedback?

A

A loop where a stimulus causes the perpetuation of an end result.

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3
Q

What is a negative feedback?

A

A loop where a stimulus causes the eventual termination of a result.

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4
Q

What feedback regulation has an active loop?

A

Positive feedback

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5
Q

What feedback regulation has an inactive loop?

A

negative feedback

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6
Q

Which feedback regulation downstream response suppresses the signal?

A

Negative feedback

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7
Q

Which feedback regulation downstream response enhances the signal?

A

Positive feedback

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8
Q

When referring to cell sensitivity, adaptation….

A

Responds to various types of stimuli and environmental changes

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9
Q

When referring to cell sensitivity desensitization….

A

Prolonged exposure to a stimulus decreases the cells response to a stimulus

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10
Q

Responds to various types of stimuli and environmental changes.

A. Adaptation
B. Desensitization

A

A. Adaptation

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11
Q

Prolonged exposure to a stimulus decreases the cell’s response to a stimulus.

A. Adaptation
B. Desensitization

A

B. Desensitization

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12
Q

GPCR’s are 7-pass transmembrane proteins, which side of the receptor will bind to a G protein?

A

Cytoplasmic side

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13
Q

Where will molecules that GPCRs recognize to be small bind?

A

bind DEEP into a pocket of the receptor

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14
Q

GDP is bound to the active site of:

A. Active G protein
B. Active GPCR
C. Inactive G protein
D. Inactive GPCR

A

C. Inactive G protein

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15
Q

Inactive G-protein has ____ bound to the active site.

A. GTP
B. GDP
C. GEF
D. GAP

A

B. GDP

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16
Q

Activated GPCR G-protein stimulates the exchange of____ for____.

A. GDP, GTP
B. GTP, GDP
C. GEF, GAP
D. GAP, GEF

A

A. GDP, GTP

17
Q

G-protein will dissociate from what when activated?

A

dissociates from GPCR and Beta-gamma complex

18
Q

What is the regulator for G-protein signaling?

A

alpha-subunit

19
Q

All or nothing respinses in frog oocytes is due to the positive feedback from what hormone?

A

progesterone

20
Q

Enzymes activated by G-protein will do what to second messengers?

A

Amplify the signal
(Increase the concentration of the second messenger)

21
Q

What is cAMP’s response to an extracellular signal?

A

Rapid rise of cAMP