CH. 16 INNATE IMMUNITY Flashcards
(39 cards)
IMMUNITY?
ABILITY TO WARD OF DISEASE
lack of resistance to a disease?
Susceptibility
defenses against any pathogen; rapid, present at birth prevents entry of microorganisms
Innate immunity (NON SPECIFIC)
immunity or resistance to a specific pathogen; slower to respond, has memory component
Adaptive immunity (SPECIFIC)
Toll-like receptors (TLRs) on host cells attach to ?
pathogen-associated molecular patterns (PAMPs)
induce the release of cytokines from the host cell that regulate the intensity and duration of immune responses
physical factors
inner portion made of connective tissue
DERMIS
physical factors
outer portion made of tightly packed epithelial cells containing keratin, a protective protein
Epidermis
physical factors
T/F Shedding and dryness of skin inhibits microbial growth?
true
physical factors
Epithelial layer that lines the gastrointestinal, respiratory, and genitourinary tracts
mucous membrane
role of mucus in line of defense?
viscous glycoproteins that trap microbes and prevent tracts from drying outucus
role of lacrimal apparatus
drains tears and washes the eye
physical factors
role of Ciliary escalator
transports microbes trapped in mucus away from the lungs
role of ear wax
prevents microbes from entering the ear
role of urine?
cleans the uretha via flow
physical factors
role of vaginal secretions
move microorganisms out of the vaginal tract
physical factors
what are the other ways to remove microbes
Peristalsis, defecation, vomiting, diarrhea
Chemical Factors
forms a protective film and lowers the pH (3–5) of skin
sebum
chemical factors
in perspiration, tears, saliva, and urine destroys bacterial cell walls
lysozome
chemical factors Low pH (1.2–3.0) of..destroys most bacteria and toxins?
gastric juice
chemical factors Low pH (3–5) of ..?
inhibits microbes
role of Normal Microbiota and Innate Immunity?
compete with pathogens via microbial antagonism (competitive exclusion)
factors of Normal Microbiota?
Competitive advantage for
space and nutrients
Produce substances harmful to pathogens
Alter conditions that affect pathogen survival
Normal Microbiota and Innate Immunity:
one organism benefits while the other (host) is unharmed
Commensalism
Normal Microbiota and Innate Immunity:
live microbial cultures administered to exert a beneficial effect
Probiotics
like yogurt
or drinks that contain live culture