CH. 16 INNATE IMMUNITY Flashcards

(39 cards)

1
Q

IMMUNITY?

A

ABILITY TO WARD OF DISEASE

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2
Q

lack of resistance to a disease?

A

Susceptibility

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3
Q

defenses against any pathogen; rapid, present at birth prevents entry of microorganisms

A

Innate immunity (NON SPECIFIC)

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4
Q

immunity or resistance to a specific pathogen; slower to respond, has memory component

A

Adaptive immunity (SPECIFIC)

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5
Q

Toll-like receptors (TLRs) on host cells attach to ?

A

pathogen-associated molecular patterns (PAMPs)

induce the release of cytokines from the host cell that regulate the intensity and duration of immune responses

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6
Q

physical factors

inner portion made of connective tissue

A

DERMIS

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7
Q

physical factors

outer portion made of tightly packed epithelial cells containing keratin, a protective protein

A

Epidermis

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8
Q

physical factors

T/F Shedding and dryness of skin inhibits microbial growth?

A

true

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9
Q

physical factors

Epithelial layer that lines the gastrointestinal, respiratory, and genitourinary tracts

A

mucous membrane

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10
Q

role of mucus in line of defense?

A

viscous glycoproteins that trap microbes and prevent tracts from drying outucus

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11
Q

role of lacrimal apparatus

A

drains tears and washes the eye

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12
Q

physical factors

role of Ciliary escalator

A

transports microbes trapped in mucus away from the lungs

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13
Q

role of ear wax

A

prevents microbes from entering the ear

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14
Q

role of urine?

A

cleans the uretha via flow

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15
Q

physical factors

role of vaginal secretions

A

move microorganisms out of the vaginal tract

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16
Q

physical factors

what are the other ways to remove microbes

A

Peristalsis, defecation, vomiting, diarrhea

17
Q

Chemical Factors

forms a protective film and lowers the pH (3–5) of skin

18
Q

chemical factors

in perspiration, tears, saliva, and urine destroys bacterial cell walls

19
Q
chemical factors
Low pH (1.2–3.0) of..destroys most bacteria and toxins?
A

gastric juice

20
Q
chemical factors
Low pH (3–5) of ..?
A

inhibits microbes

21
Q

role of Normal Microbiota and Innate Immunity?

A

compete with pathogens via microbial antagonism (competitive exclusion)

22
Q

factors of Normal Microbiota?

A

Competitive advantage for
space and nutrients
Produce substances harmful to pathogens
Alter conditions that affect pathogen survival

23
Q

Normal Microbiota and Innate Immunity:

one organism benefits while the other (host) is unharmed

24
Q

Normal Microbiota and Innate Immunity:

live microbial cultures administered to exert a beneficial effect

A

Probiotics
like yogurt
or drinks that contain live culture

25
are residents in tissues and organs
Fixed macrophages
26
roam tissues and gather at sites of infection
free macrophages
27
Chemical signals attract phagocytes to microorganisms
chemotaxis
28
Attachment of a phagocyte to the surface of the microorganism
adherance
29
microorganism is coated with serum proteins, making ingestion easier
Opsonization (ingestion)
30
Microorganism is digested inside a phagolysosome
Digestion
31
what do cytokines release during a fever? and what do they do?
prostaglandins | reset the hypothalamus to a higher temperature
32
cytoplasmic body formed by the fusion of a phagosome with a lysosome in a process that occurs during phagocytosis.
Phagolysosome
33
a fibrous protein forming the main structural constituent of hair, feathers, hoofs, claws, horns, etc
keratin
34
phago means to ?
eat
35
cyte?
denaturing mature cell
36
how is a fever beneficial?
a fever can help your child's body fight off infection | Many illness-causing microbes do best at the body's normal temperature.
37
The purpose of germ free mice in microbiome research
In this case the researcher is seeking to understand how an individual or combination of known bacteria affect the host, interact with each other, or are affected by the host.
38
Differentiate phagocyte from the process of phagocytosis
Phagocytosis occurs after the foreign body, a bacterial cell, for example, has bound to molecules called "receptors" that are on the surface of the phagocyte. The phagocyte then stretches itself around the bacterium and engulfs it
39
12. State the antiphagocytic factors used by pathogens such as
glycocalyx, leukocidins, antigenic variation, etc.