ch. 21 in class notes Flashcards

(54 cards)

1
Q

fluid medium, vital transport functions, electrolytes, metabolic wastes

A

plasma

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2
Q

RBC, WBC (granulocytes/agranulocytes), platelets

A

formed elements

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3
Q

plasms % water

A

90-91

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4
Q

plasma protein percent

A

6.5-8

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5
Q

plasma solute percent

A

2

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6
Q

transport medium
heat distribution
pH and electrolyte balance
plasma proteins differentiate from interstitial fluid

A

plasma function

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7
Q

loss of plasma proteins cause

A

sepsis

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8
Q

loss of blood cause

A

shock

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9
Q

loss of albumin takes water into intersitium with it causes distortion of blood binding when 30% of blood is lost

A
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10
Q

wbc make up what percent of blood

A

less than 1

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11
Q

plasma proteins with the functions:
osmotic pressure
carrier function

A

albumin

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12
Q

plasma proteins with the functions:
alpha and beta transport
antibody immunity

A

globulins

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13
Q

plasma protein function:
clot formation precursor

A

fibrinogen

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14
Q

why is this patient edematous:
58 year old male with alcoholic cirrhosis
presents with-
ascites
peripheral edema
labs show
serum albumin 2.1 g/dL (low)

A

leaking into plasma causing swelling into body. low albumin collapsed the oncotic pressure. leaves vessels and accumulates

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15
Q

serum does not have

A

fibrinogen

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16
Q

has fibrinogen

A

plasma

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17
Q

in healing burns. healing level is based on this. may prefer to give this and not transfusion to help heal burns helps heal faster

A

albumin levels

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18
Q

make up what percent. globulins. alpha beta gamma

A

38%

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19
Q

beta globulins (they are antibodies) are responsible for

A

transporting iron and copper

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20
Q

why we measure albumin in ICU

A

potential of shock in pts. also avoiding based on: give diuretics or paracentesis or give albumin infusion that affect albumin

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21
Q

the only true cells int eh blood

A

white blood cells

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22
Q

plasma-fibrinogen

23
Q

bioconcave
anucleate
120 day lifespan
contain hemoglobin for o2/co2 exchange
deformable to fit capillaries
not small enough to go through glomeruli unless pathology can leak

24
Q

diameter of rbc

25
5 types of granulocyte wbcs
neutrophils eosinophils basophils monocytes lymphocytes
26
function in immunity, inflammation, surveliance
WBC granulocytes
27
bacteria/fungi defense, short-lived, band forms in infection
neutrophils
28
percent neutrophils
55-65
29
allergy, parasites, asthma
eosinophils
30
percent eosinophils
1-3
31
histamine, hypersensitivity, have heparin* key layer in hypersensitivity
basophils
32
percent of basophils
less than 1%
33
b cells t cells nk cells
lymphocytes
34
percent lymphocytes
20-30%
35
bone marrow pushes out immature bands (in progression of stem cell to granulocyte) because there is high demand from systemic infection. there is a threat...in eosinophil allergies with histamine
lift shift
36
percent monocytes
3-8%
37
never let monkeys eat bannanas
neutrophils lymphocytes monocytes eosinophils basophils
38
lymphocytes are what immunity
innate?
39
platelets are cell fragments from
megakaryocytes
40
form primary platelet plug, releasing clotting factors. live 8-12. stick swell secrete
platelets/thrombocytes
41
band neutrophils in infection: 64 year old male with diabetes presents with fever and confusion labs show WBC 22,000 with 20% bands what is the significance of the bands? why are they elevated? what's a left shift?
systemic infection so quickly pushing out bands. bandemia
42
in the embryo hematopoiesis is produced
yolk sac
43
in fetal hematopoiesis is in
liver/spleen
44
postnatal, hematopoiesis is in the
bone marrow
45
seen in myelofibrosis, severe anemia, hemoglobulinopathies
extramedullary blood formation in liver and spleen in disease states
46
myeloid stem cells can become
rbc platelets granulocytes monocytes
47
lymphoid stem cells become
b cells t cells NK cells
48
increase RBCs- kidney
EPO erythopoeitin
49
increase platelets- liver
TPO (thrombopoietin)
50
increase neutrophils used in neutropenia
G-CSF
51
multilineage effects
IL-3, IL-6, GM-CSF
52
measures how fast rbc fold into tube over 1 hr
esr
53
more fibrinogen cause cells to be heavier cause it to settle much faster. ESR rate in this case is...?
54