Ch28, Tumors Flashcards Preview

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Flashcards in Ch28, Tumors Deck (78)
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1

Location of primary tumors in adults

cerebral cortex
above tentorium

2

Lcoation of priamry tumors on children

posterior fossa
below tentorium

3

single lesion;
also associated with what other clinical finding?

primary tumor

striking edema

4

multiple lesions

metastasis; not a primary tumor

5

___% of adult primary tumors are infiltrating astrocytomas

80%

6

Age of onset of infiltrating astrocytoma

40-60yo

7

Presenting signs of infiltrating astrocytoma

seizure, HA, focal neuro deficity

8

Types of infiltrating astrocytoma

diffuse astrocytoma (2/4)
anaplastic astrocytoma (3/4)
glioblastoma (4/4)

9

Glioblastioma (4/4) morphology

necrotic edges >> pseudopalisading

10

GFAP

intermediate filament present in glial cells in Glioblastioma (4/4)

11

Glioblastioma (4/4) prognosis

15 months and 25% alive at 2 years

12

Pilocytic astrocytoma location

floor/wall of 3rd vent
optic nerve
cerebral hemishpheres

13

Pilocytic astrocytoma age group

children, YA

14

Pilocytic astrocytoma gross morphology

mural nodile in wall of cyst, posterior fossa

15

Rosenthal fibers and microcysts present in ____ astrocytoma

Pilocytic astrocytoma

16

Location of pleomorphic xanthoastrocytoma (2/4)

temporal lobe of young pt

17

Pleomorphic xanthoastrocytoma
Infiltrating astrocytoma
Oligodendroglioma
Dysembryoplastic neuroepothelial tumor

seizures

18

Age by which most BS Gliomas occur

20yo

19

1. Pontine glioma
2. Tectal gliomas
3. Cortocomedullary junciton tumors

(Location) of most to least aggressive BS gliomas

20

Morphology - Calcification tumor in white matter
Location - Frontal lobe
Seizure presenteation
Mid life; 5-15% of gliomas

Oligodendroglioma

21

Age of oligodendroglioma onset

midlife (5-15%)

22

Oligodendroglioma is d/t loss of heterozygosity in what chromosomes?

1p
19q

23

Ependymoma:
Age + Most common location (for adults and children

0-20yo + 4th ventricle
Adults + SC central canal

24

Ependymoma:
if not radiated correctly, growth down thru 4th vent >> ventricular space blockage = ??

hydrocephalus

25

adult ependymoma associated with which NF?

NF2

26

Myxopapillary ependymoma location

distal SC, philum terminale

27

Paraventriculat mass lesions:
solid, may be calcified, attached to ventricular slinign

subependymoma

28

Ependymoma
Subependymoma
Choroid plexus papilloma
Colloid cysts of 3rd vent
Medulloblastoma

hydrocephalus

(colloid cysts of 3rd vent = noncomminicating)

29

most common CNS tumor of mature neurons

Ganglioma

30

rare, low grade childhood neoplasm often presenting as a seizure disorder;

Dysembryoplastic neuroepothelial tumor