Ch.3 Flashcards

1
Q

what are the basic structures of a neuron

A

cell body (soma), dendrites (collect info from other cells), axon (carries messages to neurons)

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2
Q

what is a dendritic spine?

A

protrusion from a dendrite that increases its surface area and is typical point of contact for other cells

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3
Q

axon hillock

A

juncture of soma and axon where action potential begins

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4
Q

axon collaterals

A

branches of an axon

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5
Q

telodendrion

A

end branches of an axon

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6
Q

terminal button

A

knob at tip of axon that conveys info to other neurons (also called end foot)

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7
Q

synapse

A

gap between neurons

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8
Q

what are the three types of neurons

A

sensory, motor, and interneurons

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9
Q

sensory neurons

A

carry info from sensory receptors in or on the body to the spinal chord

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10
Q

motor neurons

A

send signals from the brain and spinal cord to muscles

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11
Q

interneurons (association neurons)

A

associate sensory and motor activity within the central nervous system

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12
Q

what do bipolar neurons do?

A

transmit afferent sensory info from retinas light receptors to neurons that carry info to brains visual centers

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13
Q

what is the purpose of somatosensory dendrite and how does it do this?

A

connects directly to its axon so the cell body sits to one side of this long pathway

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14
Q

what are the 3 interneurons

A

stellate, pyramidal cell, purkinje cell

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15
Q

stellate cell

A

star shapes, small with many dendrites that extend around cell body

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16
Q

pyramidal cell

A

has long axon, a pyramid-shaped cell body, two sets of dendrites apical and basal

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17
Q

purkinje cell

A

a distinctive interneuron with extremely branched dendrites that form a fan shape

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18
Q

where do motor neurons reside

A

in the lower brainstem and the spinal cord

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19
Q

what are the three organizational aspects of neurons

A

input, association, and output

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20
Q

(glial cell) ependymal cell

A

small ovoid, found in walls of ventricles, make and secretes cerebrospinal fluid

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21
Q

(glial cell) astrocyte

A

star shaped, gives neurons structural support, transport substances between blood-brain barrier, forms scar tissue, fuels active brain areas

22
Q

microglial cell (glial cell)

A

small, derived from blood, defensive function to remove dead tissue (phagocytosis)

23
Q

(glial cell) oligodendroglial cell

A

forms myelin around CNS axons in brain and spinal chord

24
Q

(glial cell) schwann cell

A

wraps around peripheral nerves to form myelin in axons

25
myelin
glial coating tha surrounds axons
26
multiple sclerosis (MS)
nervous system disorder associated with loss of myelin
27
how are neurons repaired
schwann cells shrink then divide to form glial cells along axons former path, neuron sends out axon sprouts and finds schwann cell path to become new axon
28
what determines a cells characteristics and functions?
a cells proteins, water, salts, and ions as well
29
what does the cell membrane do?
separates intracellular and extracellular fluid, regulates movement of things in and out of cell, and is mad up of phospholipids
30
chromosome
2x stranded molecule of DNA
31
ribosomes
protein structures that act as catalysts for protein synthesis
32
translation
where messanger RNA travels from nucleus to ER where mRNA is translated into amino acid sequences to form protien
33
transcription
DNA strands unwind and a complimentary strand of mRNA is produced
34
what does an amino acid consist of?
central carbon atom bound to hydrogen atom, amino group, carboxyl group and a side chain linked together by peptide bond
35
golgi bodies
package proteins in vesicles (membranes) and give them a label as to where they should go
36
microtubules
transport the vesicles to their destinations inside or outside of the cell
37
tay-sachs disease
inherited at birth, caused by loss of genes that encode the enzyme that breaks down fatty substances, results in intellectual disability, physical changes and death by 5yrs
38
huntington disease
causes by increase in number of CAG on chromosome 4 autosomal disorder, cognitive+motor disturbances
39
what do genetic disorders result from
aberration of a chromosome --> not a single defective allele
40
down syndrome
intellectual impairment and other abnormalities, occurs w/ extra copy of 21st chromosome (trisomy)
40
what are approaches to genetic engineering?
selective breeding, cloning, transgenic techniques, knockouts
41
selective breeding
alters gene expression, objective is to maintain spontaneous mutations
42
cloning
where you produce an offspring that is genetically identical to another, can be used to observe heredity and impact of environment
43
what is transgenic technique
introduction or removal of genes into embryo with knock in technology to inactivate gene
44
phenotypic plasticity
capacity of genome to express many phenotypes
45
epigenetics
the influence of environment on selection of one or another phenotype
46
what does the absence of a corpus callosum result from?
an epigenetic influence on whether trait is expressed in a particular mouse
47
what is observed in patterns of disease in identical twins?
lack of concordance (incidence of similar behavioral traits)
48
what can be viewed as a second genetic code?
epigenetics
49
what do epigenetic mechanisms influence
protein production by blocking or unblocking a gene so that it can or cant be transcribed
50
how can environment influence induce or remove one or more blocks of genes to regulate gene expression?
histone modification: DNA unwraps or stopped from unwrapping in histone DNA methylation: transcription of DNA into mRNA enabled or blocked mRNA modification: mRNA translation may be enabled or blocked