Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Misc Derm > Ch56 > Flashcards

Ch56 Flashcards

(56 cards)

Start Studying
1
Q

epidermal layer K5,14

A

basal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

epidermal layer K1,10

A

Spinous - lamellar granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

epidermal layer k2,11

A

granular - loricrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

epidermal layer 15

A

bulge cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

body site k1,9

A

suprabasal palmoplantar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

body site K6,16,17

A

palmoplantar, nail, nair, adnexal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

body site 4,13

A

mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

body site k3,12

A

cornea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

k20

A

merkel cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

k80,86

A

hair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

k19

A

stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acidic keratins are type * and K* found on chromosome ***

A

type 1
K9-20
Chr17

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Basic keratins are type * and K* found on chromosome ***

A

type 2
K1-8
Chr12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name type III keratins

A

vimentin, desmin, periperin, GFAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

name type V keratin

A

Lamin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

adhesive points between cells

A

desmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

As a response to an injury the *** cells may migrate out to form new epidermis

A

bulge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

caused by loss of TG1

A

lamellar ichthyosis and CIE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Most important part of gene is *** which are crucial for filament elongation

A

helix initiation/ termination motifs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

hair or skin? K9-28

A

skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

hair or skin? K31-40

A

hair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

hair or skin? K1-8

A

skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

hair or skin? K71-86

24
Q

*** is crucial to epidermal differentiation

25
p63 maintains *** expression & represses cell cycle inhibitors
K5,14
26
K1 expression & cessation of cell cycling are regulated by 2 genes:
p63 isoform deltaNp63a and Notch
27
*** crucial to inducing differentiation (increases from basal to cornified layers)
Calcium
28
CE:cross linking of keratin and fillagrin by
loricrin
29
enzyme of proliferative activity in the basal layer
ornithine decarboxylase
30
ornithine decarboxylase is stimulated by
trauma, UV, estrogen, EGF, beta agonists, tumor promoters
31
ornithine decarboxylase is inhibited by
retinoids, steroids, protein deprivation
32
what keratins found in transitional boundaries of basal layer
K5/14 and k19
33
Keratin filaments insert into *** and attached to the BM
desmosomes and hemidesmosomes
34
***% of basal cells are stem cells
10%
35
Ceraminds found in which layer?
spinous layer
36
in spinous layer, what keratins are synthesized
K1,10
37
what keratins found in AKs, psoriasis, wound healing
K6,16
38
keratins of hyperproliferative states in spinous layer
K6, 16, Ki67, intergrin
39
lamellar granules diseases
Harlequin fetus and X-inked ichthyosis, CIE
40
*** bonds in TG makes CE insoluble
gamma glutamyl lysine isopeptide
41
Psoriasis: *** Involucrin, *** loricrin/fillagrin
Psoriasis: high Involucrin, low loricrin/fillagrin
42
TG***:lamellar ichthyosis, non-bulbous CIE
TG1
43
TG***: fetal epidermis
tg2
44
TG***:cross links the CE (Ca dependent), hair, DH
TG3
45
disease of Hypogranulosis:
Ichthyosis vulgaris
46
disease of hypergranulosis:
Lamellar ichthyosis, Psoriasis
47
corneal layer forms when *** is converted to ***
forms when profillagrin converted to fillagrin
48
profillagrin conversion is dependent on
calcium
49
fillagrin degrades into
urocanic acid (UV block(
50
corneal layer has *** bonds that act like glue
disulfide
51
bricks of corneal layer
protein rich corneocytes
52
mortar of corneal layer
loricrin and lamellar lipid rich ECM
53
granular layer water barrier
adherens junctions
54
adherens junctions made of
E(verywhere) and P (basal) cadherins
55
protein of adherens junctions
armadillo
56
tight junctions
zolula occludens

Misc Derm (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions