Chap 17

Question 1

ketone/aldehyde + ketone/aldehyde
NaOH, H2O

Answer 1

aldol addition - B-hydroxy

Question 2

ketone/aldehyde + ketone/aldehyde
NaOH, H2O
HEAT

Answer 2

aldol condensation - a-B-unsaturated compound

Question 3

what type of mechanism is the aldol condensation

Answer 3

e1cb

Question 4

what happens in e1cb mechanism

Answer 4

enolate forms after the b-hydroxy forms

Question 5

1,3-dicarbonyl + a-B-unsaturated
NaOH, H2O

Answer 5

Micheal. adds unsaturated at beta

Question 6

2 eq of esters
1. NaOR, HOR -or- CH3ONa
2. H+ -or- HCl

Answer 6

claisen. forms B-ketoester

Question 7

1 diester
1. NaOR, HOR
2. H+

Answer 7

Diekmann. cyclic B-ketoeter

Question 8

if there are 2 alpha protons which will be removed?

Answer 8

less substituted

Question 9

1,3-dicarbonyl + a-B-unsaturated
NaOH, H2O
HEAT

Answer 9

Robinson ring. forms a ring.whi

Question 10

which alpha proton will be removed in Robinson ring

Answer 10

the one that makes a favorable ring (6)

Question 11

acetoacetic

Answer 11

1,3 dicarbonyl with one O- group

Question 12

acetoacetic
HCl, H2O
HEAT

Answer 12

decarboxylation - KETONE

Question 13

Malonic ester

Answer 13

1,3 dicabronyl with 2 o group

Question 14

Malonic ester
HCl, H2O
HEAT

Answer 14

decarboxylation - CARBOXLIC ACID