Chap. 2- Development Flashcards

(39 cards)

1
Q

What is the wall of the primitive neural tube called?

A

Germinal neuroepithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the primitive neural tube made up of?

A

Periventricular and subpial zone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the cells of asymmetric division?

A

Radial glial cells, basal progenitor and neuroblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What does a radial glial cell produce?

A

More radial glials, basal progenitors and neuroblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What do nasal progenitor cells produce?

A

Astrocytes, oligodendrocytes and neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Where does tangential migration happen and what happens?

A

Neuroblasts move parallel to pial surface to remain subpial or deeper.
- Rhombic lips with cerebellum, midbrain- substantia nigra, brainstem- cuneate, olivary, pontine and tegmental reticular nuc, spinal cord and tel with basal nuclei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where is the process of neurogenesis and neuronal migration throughout adult life?

A

Subventricular zone and in granular cell layer of dentate gyrus in hippocampus
Precursors are glial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where is the mantle layer in the spinal cord?

A

Newly formed cells migrate to establish this layer around the neural tube
- formed by neurons and glia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What layer becomes the white matter in spinal cord?

A

Marginal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does the underlying germinal epithelium become in spinal cord?

A

Ventricular or ependymal layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What half is sensory and what is motor in spinal cord and in mantle layer?

A

Dorsal- sensory- alar
Ventral- motor - basal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What makes division between alar and basal?

A

Sulcus limitans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What marks the division between tel and di?

A

When optic vesicles develop and the pros vesicle begins to develop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does the rhomb become?

A

Met and mye
Met is pons and cerebellum
Mye is medulla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the three flexures that form in order?

A
  1. Mesenchephalic- ventral
  2. Cervical
  3. Pontine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where are the dendrites and axons of the purkinje cells?

A

Dendrites- molecular layer
Axons- directed to nuclei

17
Q

Where do the choroid plexus develop?

A
  • medial aspect of each developing telencephalic vesicle
  • roof of the third and fourth ventricles
18
Q

What is the tela choroidea?

A

Where pia mater contact ependymal cell layer
This and blood caps form the choroid

19
Q

Where is the choroid located?

A
  • inside lateral ventricles and extend through interventricular foramen to third ventricle and on its roof
  • more develop on fourth ventricle causally to caudal medullary velum
20
Q

What forms the somitomeres?

A

Paraxial mesoderm

21
Q

What does the somitomere that is lateral to the developed encephalon form?

A

Cranial muscles, most of the neurocranium and dermal and meningeal tissues

22
Q

What does the neural crest in the head contribute to?

A

Formation of the splanchnocranium with the mandible and hyoid bone, connective tissue of head muscles and to wall of blood vessels

23
Q

What does the somitomere become caudal to the seventh one?

24
Q

What are the three regions of a mature somite?

A

Dermatome, sclerotome, and myotome

25
What does dermatome give rise to?
Dermis and subcutaneous tissue
26
What does sclerotome give rise to?
Vertebrae and ribs
27
What does myotome give rise to?
Axial, thoracic, abdominal and limb striated muscle
28
What do the parts of the sclerotome become?
Ventral - vertebral body and ribs Lateral - vertebral arch Cranial - annulus fibrosis and end plate
29
What do the spinal cord neural crest cells give rise to?
Sensory neurons and spinal ganglia
30
What do the first 4 sclerotomes become?
Occipital and otic regions
31
Fourth and fifth sclerotomes
Proatlas
32
What does the proatlas become?
Anterior- occipital condyles Posterior- articular surfaces of atlas and apex of dens
33
Fifth and sixth sclerotomes
Mesenchyme form primordial body of atlas and dens
34
Sixth and seventh sclerotomes
Body of axis
35
Seventh and eighth sclerotomes
C3 vert
36
How do the cervical spinal nerves exit?
Cranially to the vertebrae with the same number
37
How does a vertebral malformation happen?
When homologous sclerotome fails to develop or there is failure in chondrification or ossification centers of vertebral body
38
What is the absence of the whole body of the vertebra?
Asomia (agenesis)
39
How does a butterfly vertebra happen?
When the notochord fails to disappear at the body of the vertebra