Flashcards in chapter 1 fetal lung development Deck (23)
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1
what are the fetal lung development requirements
adequate surface area, pulmonary vascular systems ability to transport blood through the lungs, structure and elasticity
2
stages of lung development
embryonal
pseudoglandular
canalicular
saccular
alveolar
3
how long is the embryonal stage
week 1 - 8
4
when is the pseudo glandular stage
week 8-16
5
what lung developments occur during the pseudo glandular stage
conducting airways develop, pattern of lung structure is formed, cilia goblet cells, and mucus glands are formed, the epiglottis and the membrane that separates oropharnx is formed
6
when is the canalicular stage
week 17-26
7
what stage does fetal viability occur in and what week
canalicular stage week 22
8
what is developed (lungs) during week 20-22
type 1 and II epithelial cells, immature surfactant, and smooth muscle in conducting airways
9
when is the saccular stage
week 27 - 35/36 weeks & post term
10
when are alveoli seen
week 32
11
what occurs in the lungs during the saccular stage
alveoli epithelium and pulmonary capillaries merge, alveoli increase in number and size, mature surfactant
12
what occurs during alveolar stage
at birth alveoli are 20-150 million, and continue development up to age 8 increasing in size until growth of chest wall is complete
13
what factors affect lung growth
hypoxia, starvation, hyperoxia
14
what is pulmonary hypoplasia
lack of alveoli, not enough airways, olighydramnios (not enough amniotic fluid)
15
what can cause pulmonary hypoplasia
diaphragmatic hernia
16
what is the function of type I cells
allows for gas diffusion, and used as a barrier against water and solute leakage
17
what is the function of type II cells
surfactant production, storage and secretion
18
what is surfactant made up of
pc, pg, neutral lipids, and proteins
19
what law describes surfactant and what is its purpose
lap laces law; and to lower surface tension
20
when is surfactant inhibited
hypoxia, hypothermia, acidosis
21
how much fluid does fetal lungs secrete
250-300 ml per day
22
when are fetal lungs filled with fluid
cannicular period until delivery
23
