Chapter 1 Information, Sources, Regulatory Agencies, Drug Legislation, and Prescription Writing

Question 1

Pharmacotherapy

Answer 1

The use of medications to treat different disease states

Question 2

Pharmacodynamics

Answer 2

The study of the action of drugs on living organisms

Question 3

Pharmacokinetics

Answer 3

The study of what the body does to a drug; the measurement of the absorption, distribution, metabolism, and excretion of the drug from the body

Question 4

Pharmacy

Answer 4

The practice of compounding, preparing, dispensing, and counseling of patients about their medications

Question 5

Toxicology

Answer 5

The study of the harmful effects of drugs on living tissues

Question 6

Chemical name

Answer 6

Determined by the chemical structure of the compound

Question 7

Trade name

Answer 7

Name company puts on drug

Question 8

Generic name

Answer 8

Shortened version of chemical name

Question 9

1914: Established regulations governing use of opium, opiates, and cocaine
1937: Marijuana laws added

Answer 9

Harrison Narcotic Act

Question 10

Takes 12 years and 350 million from the time a drug is synthesized in the lab to its availability on product shelves. True or false?

Answer 10

True

Question 11

Phase 1 of clinical studies

Answer 11

• Small and then increasing doses are
  administered to a limited number of healthy human volunteers
• Determines biologic effects, metabolism, safe dose range in humans, and toxic effects of the drug

Question 12

Phase 2 of clinical studies

Answer 12

• Larger groups of humans are given the drug
• Adverse reactions are reported to the FDA

Question 13

Phase 3 of clinical studies

Answer 13

• Clinical evaluation involving a large number of patients who have the condition for which the drug is indicated takes place
• Safety and efficacy must be demonstrated - Dosage is determined

Question 14

Phase 4 of clinical studies

Answer 14

• Post marketing surveillance
• Toxicity that occurs in patients taking the drug after it is released is recorded

Question 15

How many schedules of controlled substances are there?

Answer 15

6

Question 16

Packaging Inserts PI

Answer 16

• Chemical makeup of drug
• FDA-approved indications for use
• Contraindications
• Warnings
• Adverse reactions
• Drug interactions
• Dose and administration
• How supplied

Question 17

• Draw attention to safety concerns
  associated with the drug
• Educates both prescriber and patient about serious safety concerns associated with the drug

Answer 17

Blackbox warning

Question 18

Use is used outside the stated FDA
indications

Answer 18

Off-label use

Question 19

Indicates that the FDA has
approved the drug for specific use

Answer 19

Labeled use

Question 20

300mg and 350mg Acetaminophen are the same amounts. True or False?

Answer 20

True

Question 21

Primary measurement system used in the pharmacy is?

Answer 21

Metric system

Question 22

Solid drugs are dispensed by?

Answer 22

Weight (mg)

Question 23

Liquid drugs by?

Answer 23

Volume (mL)

Question 24

Prescription format:

Answer 24

• Heading
• Body
• Closing
• Substitution