Chapter 1- Pathophysiology for the Health Professions Flashcards

(69 cards)

1
Q

Pathophysiology

A

Studies some aspects of pathology, the cell and tissue changes associated with disease. Focuses on the loss or change in normal structure and function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Disease

A

Deviation from normal structure or function of any part, organ, system, or from a state of wellness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Homeostasis

A

Maintenance of a relatively stable internal environment regardless of external changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Seven steps to health

A
  • Non-smoker; avoid 2nd hand smoke
  • Eat 5-10 servings of vegetables and fruits per day, eat foods that are high in fiber and low in fat, and if you drink alcohol, limit consumption to about 1-2 glasses per day
  • Physically active on a regular basis; maintain a healthy body weight
  • Sun protection
  • Cancer screening guidelines
  • Visit doctor and dentist regularly and for changes
  • Use health and safety instructions regarding using, storing, and disposing of hazardous materials
  • Normal values; aren’t absolute; may adjust for age, gender, genetics, environment, and activity level
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

CDC

A

Collects data on all types of disease and gives evidence-based recommendations for prevention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Primary prevention

A

The goal is to protect healthy people from developing disease or experiencing injury initially. Includes regular exercise, seat belts, immunizations, drug/tobacco/alcohol educations, regular exams and screening tests for risk factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Secondary prevention

A

Occur after illness or serious risk factors are present. Goal is to stop or slow progress of disease in early stages. Includes taking daily ASA to prevent second heart attack, regular exams and screening for known risk factors, and modified work for injured workers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Tertiary prevention

A

Helping those manage complicated, long-term health problems; diabetes, heart disease, CA, chronic musculoskeletal disease. Includes cardiac and stroke rehab, chronic pain management programs, and patient support groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Medical history components

A

Prior illness, allergies, hospitalizations, treatment, therapy, supplements, medications, herbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Medical history influencing factors

A

Age, ethnicity, culture, presence of chronic disease, community, environment, family, significant other (support)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Diagnosis

A

Signs and symptoms, laboratory tests, radiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Etiology

A

Causative factors. Congenital, inherited, genetic, viruses, bacteria, immune, metabolic, degenerative, changes, malignancy, burns and other trauma, environmental, and nutritional deficiencies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Idiopathic

A

Cause of disease is unknown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Iatrogenic

A

Treatment, procedure, or an error may have caused the disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Predisposing factors

A

Tendencies that promote the deviation of the disease; age, gender, inherited factors, occupational exposure, certain dietary practices

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Prophylaxis

A

Preserve health and prevent the spread of disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Prevention

A

Linked to etiology and predisposing factors; vaccinations, dietary and lifestyle modifications, removal or harmful materials in environment, stop harmful activities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Pathogenesis

A

Development of the disease, sequence of events involved in tissue changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Onset

A

May be sudden or insidious (gradual progression with mild or vague signs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Acute disease

A

Short term illness that develops quickly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Chronic disease

A

Milder condition develops gradually

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Subclinical state

A

Pathologic changes occur but there aren’t any symptoms yet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Latent “silent stage”

A

No clinical signs yet. Called incubation period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Prodromal period

A

Person becomes aware of changes in the body but signs are non-specific; fatigue, loss of appetite, headache. Lab tests are negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Manifestations of disease
Signs and symptoms
26
Signs
Observable
27
Symptoms
Subjective
28
Lesion
Change in the tissue; microscopic such as cells or blister on skin
29
Syndrome
Collections of signs and symptoms often affecting more than one organ
30
Diagnostic tests
Lab tests that help diagnose the disease. Also help to monitor the disease
31
Remission
When manifestations stop; either permanently or temporarily
32
Exacerbation
Worsening in severity
33
Precipitating factor
Triggers an acute episode
34
Complications
New problems
35
Therapy
Interventions to help promote recovery or slow progress of disease
36
Sequelae
Potential unwanted outcomes of the primary condition
37
Convalescence or rehabilitation
Period of recovery and return to normal healthy state. May last several weeks or months
38
Prognosis
Likelihood for recovery or other outcomes
39
Morbidity
Disease rates within a group
40
Mortality
Deaths
41
Autopsy or postmortem exam
Find cause of death. Done by pathologist
42
Epidemiology
Science of tracking the pattern of the disease
43
Epidemic
Higher than expected cases in a certain area
44
Pandemic
Higher numbers around globe
45
Communicable diseases
Spread from one person to another
46
Notifiable/reportable disease
Reported by MD
47
Normal tissue change
Tissue changes of breast and uterus in pregnancy; environmental changes in irritation
48
Abnormal tissue change
Irreversible changes in a cell signal a change in DNA structure or function; so need to find the cause and monitor any abnormality
49
Atrophy
Decrease size of cells
50
Hypertrophy
Increase size of cells
51
Hyperplasia
Increase number of cells resulting in enlarge tissue mass
52
Metaplasia
One mature cell type is replaced by a different mature cell type
53
Dysplasia
Tissue varies in size and shape, large nuclei frequently present, and rate of mitosis is increased
54
Anaplasia
Cells are undifferentiated with variable nuclear and cell structures and numerous mitotic figures
55
Neoplasia
New growth
56
Benign
Usually less serious, don't spread
57
Malignant
Cancer has spread
58
Apoptosis
Refers to programmed cell death (expected) or may increase in aging, cell injury, or excessive replication
59
Necrosis
Not a preprogrammed event; occurs in the presence of irreversible damage to cells, tissue, or a portion of an organ
60
Ischemia
Decreased supply of oxygenated blood to a tissue or organ due to circulatory obstruction
61
Hypoxia
Reduced oxygen in the tissue. Quickly affects cells with a high demand for oxygen
62
Anaerobic metabolism
Results from hypoxia. Causes the buildup of lactic acid. Metabolism without oxygen
63
Severe oxygen deficit
Interferes with energy production in the cell, leading to loss of the sodium pump at the cell membrane, as well as other cell functions. May lead to buildup of sodium within cell (rupture)
64
Liquefaction necrosis
Process by which dead cells liquefy under the influence of certain cell enzymes
65
Coagulative necrosis
Occurs when the cell proteins are altered or denatured, and the cells retain some form for a time after death
66
Fat necrosis
Occurs when fatty tissue is broken down into fatty acids in the presence of infection or certain enzymes. May increase inflammation
67
Caseous necrosis
Thick, yellowish, "cheesy" substance forms
68
Infarction
Applies to an area of dead cells resulting from lack of oxygen
69
Gangrene
An area of necrotic tissue, usually associated with a lack or loss of blood supply that is followed by invasion of bacteria