Chapter 10 (Muscle Tissue) Flashcards

(49 cards)

1
Q

Muscle FIbers are bundled within a

A

fascicle

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2
Q

There are ___ layers of skeletal muscle C.T. wrappings, they are___

A

3
1)Epimysium (Outermost layer… Dense Ireg.)
2)Perimysium(white spidering structure Dense Ireg.)
3)Endomysium (Inner most…Areolar)

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3
Q

There are ___ types of fascia, they are ___

A

two

1)Deep (separates individual muscles)
2) Superficial (Separates muscle From skin)

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4
Q

Skeletal is ___ and has extensive ___

A

vascularized
blood vessels

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5
Q

A muscle cell consists of ___ parts, they are ___

A

3
1) Sarcoplasm (cytoplasm)
2) Multiple nuclei
3) Sarcolemma (plasma membrane)

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6
Q

Muscle fibers are __ cell

A

one

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7
Q

Sodium which is __ charged, is the main excitatory ion.

A

positively

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8
Q

Potassium ___ down and restores the _____

A

resting membrane potential

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9
Q

The Terminal cisternae holds onto ___

A

calcium

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10
Q

Calcium binds to ___(2)

A

calmodulin
Calsequestrin

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11
Q

the pneumonic device for terminal cisternae is ___

A

treasure chest

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12
Q

Myoglib (which is a protein) holds ____

A

extra oxygen in muscle cells

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13
Q

When a motor neuron fires there is the _____ principle (everything or nothing has to contract)

A

all or none

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14
Q

A.C.H. diffused across cleft, binds to receptors, excites Fiber

A

ok

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15
Q

When thinking about muscles… the configeration of them goes ___(5)

A

1)Terminal Cisterae (holds calcium)
2)cytosol
3)T-tubule (voltage sensitive…green main tube that carries charge
4)Cytosol
5)Terminal Cistertae

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16
Q

Myofilaments are __ proteins. There are two types which are ___

A

1)contractile
2)thick (Myosin….which has myosin heads)
3)thin (twisted strand of actin that has an myosin binding site)

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17
Q

What are the two regulatory proteins in thin filaments ___

A

1) tropomyosin
2) troponin

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18
Q

Myofilaments are arranged in repeating units called __. They are delineated at both ends by ___

A

sarcomeres
Z discs

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19
Q

Sarcomere runs from ____ to ____. The ___ is the length of the thick filament. The ____ is on either side of the A band.

A

z disc
A band (thick filaments)
I band (only contains thin filament)

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20
Q

The ___ is the central portion of the A band

21
Q

The ___ is the middle of the H zone

22
Q

__ stabilized the thick filaments

A

Connection (green spiral)

23
Q

A ___ controls muscle fibers

24
Q

Small motor units allow for ___

A

precise control of force output

25
The gates that release calcium are voltage ____
sensitive
26
progression of neuromuscular junction
1) neuron excites muscle fiber by sending a nerve signal down and propagating calcium into the synaptic knob 2) calcium-binding causes vesicles to merge with the plasma membrane and ACh is exocytosed into synaptic cleft 4) ACH diffuses across the synaptic cleft to bind with ACh receptors.
27
The sarcolemma of an unstimulated skelatal muscle fiber a a RMP of ___
-90mv
28
Depolarization occurs as the ___
voltage-gated NA+ channels open and sodium enters
29
Repolarization occurs when the voltage-gated sodium channels close and sodium ____
moves out of the cell
30
tetanus is caused by the toxin
clostridium tetani (blocks the release of inhibitory neurotransmitter)
31
Botulism is caused by
clostridium botulinum (prevents the release of ACh at synaptic knobs
32
3 ways to create ATP
1) creatine phosphate 2) Glycolysis 3) Aerobic cellular respiration
33
When there is low oxygen available lactate forms from __
pyruvate (this is called lactate dehydrogenase)
34
Oxidative fibers that are fatigue-resistand are
red
35
glycolytic fibers which are fatigable are
white fibers
36
the three types of skeletal fibers are
1)slow oxidative 2) fast oxidative 3) fast glycolytic
37
ok
38
Recruitment is also called
multiple motor unit summation
39
ok
40
Isometric contraction
tension is increased by insuffcient to overcome resistance (baby)
41
Isotonic contraction
overcomes resistance
42
The tension a mucle produces depends on
the length at time of stimulation
43
Hypertrophy is when
muscle increases in size
44
atrophy is when
muscles decrease in size due to lack of use
45
calmodulin is a
protein that binds calcium to trigger contraction
46
myosin light-chain kinase (MLCK):
enzyme that phosphorylates myosin heads when activated by calmodulin
47
myosin light-chain phosphatase
enzyme that dephosphorylates myosin head (required for relaxation)
48
Myogenic response
is contraction in reaction to stretch
49
Stress-relaxation response
is relaxation after prolonged stretch