Chapter 12 Lipids Flashcards

1
Q

has polar and nonpolar region

A

amphipathic

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2
Q

palmitate structure

A

16C

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3
Q

oleate structure

A

18C cis w9

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4
Q

laurate structure

A

12C

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5
Q

Myristate structure

A

14C

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6
Q

Stearate structure

A

18C

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7
Q

Arachidate structure

A

20C

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8
Q

Behenate structure

A

22C

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9
Q

Lignocerate structure

A

24C

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10
Q

Palmitoleate structure

A

16C w9

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11
Q

linoleate structure

A

18C w9,12

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12
Q

linolenate structure

A

18C w9,12,15

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13
Q

arachidonate structure

A

20C w5,8,11,14

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14
Q

Longer fatty acids have (higher/lower) melting points

A

higher

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15
Q

more unsaturated fatty acids have (higher/lower) melting points

A

lower

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16
Q

three major types of membrane lipids

A

phospholipids, glycolipids, cholesterol

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17
Q

phosphoglyceride structure

A

glycerol with two fatty acids and one phosphate group which is in turn bound to alcohol group. All bound by peptide bonds.

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18
Q

Cause of respiratory distress syndrome

A

lack of lecithin (DPPC). Makes hard to breathe.

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19
Q

sphingosine

A

18-carbon amino alcohol with an unsaturated hydrocarbon chain. Can be used to make phospholipids.

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20
Q

more cholesterol makes membrane (less/more) fluid

21
Q

less cholesterol makes membrane (less/more) rigid

A

less rigid

22
Q

excess cholesterol precipitates and forms ?

A

gallstones

23
Q

cholesterol is the precursor of ? (3)

A

bile salts, steroid hormones, vit D

24
Q

bile salts help to break down ?

25
cortisol functions to ?
increase the glucose glucose and glycogen concentration in the body
26
increases the glucose glucose and glycogen concentration in the body
cortisol
27
? have modified their lipids to accomodate their environment
archaebacteria
28
modifications to lipids by archaebacteria
ether linkage (instead of peptide), branched chain, inverted stereochemisry
29
arachaebacteria environment
high temp, high acid, high base
30
lipid saturation (increases/decreases) melting point
increases
31
amphipathic
polar and nonpolar region
32
phospholipids and glycolipids form ?
bilayers
33
ionized fatty acids form?
micelles
34
driving force of assembly of bilayers
hydrophobic effect
35
liposome structure
bilayer membrane
36
membrane permeability is low for ? and ? molecules
charged (primary factor), large
37
? are responsible for transport of molecules across the membrane
membrane proteins
38
protein stucture that spans membranes
alpha helix (hydrophobic and nonpolar region)
39
porin structure
beta barrel
40
since porins lack ?, they do not show hydrophobic transmembrane regions
hydrophobic alpha helices
41
lipid signalling molecules
prostaglandins
42
prostaglandin synthesis starts with ?
release of a fatty acid from a membrane lipid followed by two oxidation steps
43
prostaglandin synthesis is is catalyzed by ? located in the membrane
prostaglandin H2 synthase
44
Aspirin acetylates ser530 to ?
inactivate prostaglandin H2 synthase
45
membrane components have ? mobility
lateral
46
virtually all naturally occurring fatty acids are (trans/cis)
cis
47
Na+, K+ ATPase pumps out ? and pumps in ?
pumps out Na+ and pumps in K+
48
transmembrane helices AAs have (positve/negative) delta G
positive
49
? is on red blod cells to increase polariy to dissolve in hydrophilic environment
glycophorin