Chapter 14 - Alpha Substitution Reactions of Carbonyls Flashcards Preview

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Flashcards in Chapter 14 - Alpha Substitution Reactions of Carbonyls Deck (8)
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1
Q

Halogenation of a ketone under basic conditions will form _____ while the same reaction under acidic conditions will make ____

A

tetra substituted product with halogen

mono substituted product with halogen

2
Q

Haloform Reaction

A

a ketone is treated with OH and xs halogen to form a carboxylate ion, then quenched to make COOH

3
Q

What must the starting compound be in the haloform reaction?

A

methyl ketone

4
Q

Aldol Condensation

A

aldehyde is treated with base and water to make a beta hydroxy aldehyde

5
Q

A beta hydroxy aldehyde can be treated with xs acid or base and heat to make _____

A

alpha beta unsaturated aldehyde

6
Q

Claisen Condensation

A

similar to aldol condensation

ester is treated with a base to make a beta ketone ester

7
Q

In order for formation of a beta ketone ester from an ester in the Claisen condensation, the _____ and the ____ from the starting compound must _____

A

reagent, ester group, match

8
Q

Beta Decarboxylation

A

a beta keto ester is treated with a base and heat to form a ketone