Chapter 14- Gene Expression Flashcards

(45 cards)

0
Q

Transcription

A

Synthesis of RNA using information in the DNA

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1
Q

Gene Express

A

The process in which DNA directs the synthesis of proteins

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2
Q

mRNA

A

Strand of RNA that carries genetic message from DNA to protein synthesizing part of cell

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3
Q

Translation

A

Synthesis of a polypeptide using the information in mRNA

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4
Q

Ribosome

A

Complex of particles that facilitate the orderly linking of amino acids to polypeptide chains

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5
Q

Primary Transcipt

A

The initial part of RNA that is not translated into a protein

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6
Q

Triplet Code

A

Genetic instruction for a polypeptide chai written in three nucleotide words

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7
Q

Template strands

A

Provides pattern or template for the sequence of nucleotides in a RNA transcript

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8
Q

Codon

A

mRNA nucleotide triplet

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9
Q

Reading frame

A

The triplet grouping of ribonucleotides used by translation machinery

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10
Q

RNA polymerase

A

Pries apart the stand of DNA and makes RNA form free floating nucleotides, complementary to DNA

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11
Q

Promoter

A

DNA sequence where RNA polymerase attaches and begins its thing

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12
Q

Terminator

A

The part of RNA that ends the transcription

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13
Q

Transcription unit

A

Stretch of DNA that is transcribed into a RNA molecule

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14
Q

Transcription factors

A

Collection of proteins that mediate the binding of RNA polymerase and initiation of transcription

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15
Q

Transcription initiation complex

A

Complex of RNA polymerase and transcription factors bound the promoter

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16
Q

TATA box

A

In forming the initiation at complex at a eukaryotic promoter

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17
Q

Poly-A tail

A

At the 3’ end, an enzyme adds 50-250 adds adenine nucleotides

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18
Q

RNA processing

A

Both ends of primary transcripts are altered by enzymes in Eukaryotes before the genetic messages are dispatch to the cytoplasm

19
Q

5’ cap

A

A modified form of guanine nucleotide added I tot the 5’ end after transcription of first 20-49 nucleotides

20
Q

RNA splicing

A

A cut and paste job of a large removal of RNA molecules that is originally synthesized

21
Q

Introns

A

The noncoding segments of nucleic acid that lies between coding regions

22
Q

Exons

A

The coding regions of the DNA that is expressed

23
Q

Alternative RNA Splicing

A

Genes that give rise to two or more different polypeptide depending on which segments are treated as exons during RNA processing

24
Spliceosome
A large complex of proteins and small RNA that remove introns
25
Ribozymes
RNA molecules that function as enzymes
26
tRNA
The function of tRNA is to transfer amino acids from the cytoplasmic pool of amino acids
27
Anticodon
The particular nucleotide triplet that base pairs to a specific mRNA codon
28
Aminoacyl-tRNA synthetases
The correct matching up if tRNA and amino acids is carried out ha family of related enzymes
29
Wobble
Flexible base pairing at the 5' end of tRNA anticodon can pair with either a or g at the Thrid position
30
rRNA
What the anti codons are made out of
31
P site
Where the amino acid binds to polypeptide
32
A site
Point where the tRNA is added
33
E site
Exit site
34
Signal peptide
The polypeptides of proteins that are destined for the endomembrane
35
Signal recognition particle
Functions as an escort that brings ribosome to receptor in er membrane
36
Point mutations
Change in a single nucleotide pair of gene
37
Nucleotide pair substitution
Replacement of one nucleotide and its partner
38
Silent mutations
No effect on the phenotype
39
Missesne mutations
Change one amino acid to another and have little effects on the protein
40
Nonsense mutations
Causes translations to be canceled and stops the polypeptide and make the
41
Insertions
Addition of nucleotide
42
Deletion
Loss of nucleotide
43
Frame shift mutation
When the points where the codon are placed are moved
44
Mutagen
Interact with DNA and cause mutations