Chapter 16 - Lymphatic Flashcards

1
Q

The lymphatic pathways begin as lymphatic ________.

A

capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Lymphatic ducts unite with veins in the ______.

A

thorax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lymphatic vessels transport excess fluid away from ___________ in most tissues and return it into the bloodstream.

A

interstitial spaces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Special lymphatic capillaries in the lining of the small intestine are called:

A

lacteals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Are lymphatic tubes closed ended or open ended?

A

closed-ended

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The walls of lymphatic capillaries are made of:

A

simple squamous endothelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

once inside lymphatic capillaries, fluid is called:

A

lymph

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Lymphatic capillaries merge into ______

A

lymphatic vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The walls of lymphatic veins are similar to veins but they are _______.

A

thinner

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name the 3 layers of lymphatic vessels:

A
  1. endothelial lining

2. middle layer of smooth muscle and elastic fibers, connective tissue outer layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Lymphatic vessels have _____ to prevent backflow:

A

semilunar valves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The larger lymphatic vessels lead to _____ ______.

A

lymph nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Lymphatic vessels then drain to:

A

lymphatic trunks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

There are various lymphatic trunks such as:

A
  • intestinal, jugular, bronchomediastinal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lymphatic trunks then merge to:

A

collecting ducts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Describe the pathway of lymph starting from the capillaries:

A

capillaries-afferent vessels - lymph nodes - efferent vessels - lymph trunks - ducts - bloodstream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How many lymphatic collecting ducts are there?

A

2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the lymphatic collecting ducts:

A
  • thoracic duct

- right lymphatic duct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Which collecting duct is wider and longer?

A

thoracic duct

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Where does the thoracic lymphatic duct originate?

A

cisterna chlyi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Where does the thoracic duct empty?

A

left subclavian vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Where does the right lymphatic duct originate?

A

right thorax at union of right jugular, right subclavian, right bronchomediastinal trunks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Where does the right lymphatic duct empty?

A

right subclavian vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Where does lymph end up?

A

plasma in venous system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Tissue fluid originates from plasma and includes water and dissolved substances that have passed through the blood capillary wall.

Tissue fluid generally lacks ______ but some smaller ________ are filtered out of blood capillaries into interstitial spaces.

As the protein concentration of tissue fluid increases, ________ increases.

A
  1. proteins

2. colloid osmotic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Tissue fluid originates from plasma and includes water and dissolved substances that have passed through the blood capillary wall.

Tissue fluid generally lacks ______ but some smaller ________ are filtered out of blood capillaries into interstitial spaces.

As the protein concentration of tissue fluid increases, ________ increases.

A
  1. proteins

2. colloid osmotic pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Is lymph under high or low pressure?

A

low pressure, like venous blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

When does lymphatic flow peak?

A

exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What helps lymph move through vessels?

A

skeletal muscles, breathing, smooth muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Conditions that interfere with lymph movement cause tissue fluid to accumulate in interstitial spaces causing:

A

edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Lymphatic capillaries in the small intestine play a major role in the absorption of ______:

A

dietary fats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What does lymph do with the small proteins that were filtered out of venous capillaries?

A

return it to the bloodstream eventually

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

How are the walls of lymph vessels special?

A

epithelial cells overlap but are not attached: thus creating flaplike valves in the wall: valves open when hydrostatic pressure is greater outside and close when pressure is greater inside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

The epithelial cells of the lymphatic capillary wall are also attached to surrounding ___________:

A

connective tissue cells by thin protein filaments, therefore preventing the lumen from caving in on itself when the pressure on the outside is greater

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Lymphatic tissue contains (think cells):

A

lymphocytes, macrophages and other cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

The unencapsulated diffuse lymphatic tissue associated with the digestive, respiratory, urinary and reproductive tracts is called _____.

A

MALT (mucosa-associated lymphoid tissue)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

The MALT contains masses of lymphatic tissue called:

A

lymphatic nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

What are the lymphatic nodules? Are they the same as lymph nodes?

A

tonsils and appendix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

MALT aggregates of lymphatic nodules are called _______ are scattered throughout the mucosal lining of the ______ ______.

A

peyer’s patches

small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Encapsulated lymphatic tissues includes:

A

lymph nodes, thymus and spleen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

What is different about encapsulated lymphatic tissue:

A

connective tissue capsule encloses organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Blood vessels and nerves join to exit the lymph node at the ______.

A

hilum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Fluid enters the lymph node through:

A

afferent vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Lymph node has compartments called lymphatic nodules (not to be confused with other lymphatic nodules) or _______>

A

lymphatic follicles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

The functional units of the lymph nodes are the ______>

A

lymphatic follicles/nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Within the lymphatic follicles are ______ _______, where B lymphocytes proliferate.

A

germinal centers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Spaces in a lymph node are called:

A

lymphatic sinuses

48
Q

Disease-causing agents are called:

A

pathogens

49
Q

Viruses are/are not pathogens

A

are, they are not considered organisms but they are pathogens

50
Q

General mechanisms of protection are called ______ defense:

A

innate; include mechanical barriers, chemical barriers, fever, natural killer T cells

51
Q

Precise protective mechanisms are called:

A

adaptive defense

52
Q

Adaptive defense can also be called:

A

immunity

53
Q

What develops faster, adaptive or innate defense?

A

innate

54
Q

List the innate defenses:

A

species resistance, mechanical barriers, chemical barriers, natural killer cells, inflammation, phagocytosis, fever

55
Q

Some diseases affect certain species and not others. This is known as:

A

species resistance

56
Q

First line of defense is the ______ barriers:

A

mechanical

57
Q

Lymphocytes and fibroblasts produce:

A

interferons, they resist replication of a variety of tissue and also stimulate phagocytosis

58
Q

Defensins are peptides produced by ________ and other types of granular white blood cells.

A

neutrophils

59
Q

What do defensins do?

A

make holes in bacterial walls and membranes, crippling microbes

60
Q

What do collectins do?

A

broad protection against bacteria, yeasts and viruses. Home in on slight differences in structures and arrangements of sugars

61
Q

_____ is a group of proteins in plasma and other bodily fluids, cascade reaction.

A

complement

62
Q

Where are complements synthesized?

A

liver

63
Q

________ are a small population of lymphocytes that are distinctly different from the lymphocytes that provide adaptive defense mechanisms.

A

Natural Killer (NK) cells

64
Q

NK cells secrete _________, that lyse the cell membrane.

A

perforins

65
Q

______ is a reaction that produces localized redness, swelling, heat and pain.

A

inflammation

66
Q

Why is inflamed skin red and hot?

A

red because dilated blood vessels, hot because blood from deeper (Warmer) parts of the body rushes to the area

67
Q

Inflammation is caused only by pathogens, true or false.

A

False

68
Q

What happens during inflammation:

A

swelling/redness, white blood cells invade the region, clotting, fibroblasts make new fibers, phagocytes eat old shit, new cells divide to repair

69
Q

Phagocytosis removes foreign particles from ______ and also blood.

A

lymph

70
Q

The most active phagocytic cells are ______ and ______

A

neutrophils (engulf smaller) and monocytes (engulf larger particles)

71
Q

What describes chemicals released from injured areas attracting cells:

A

chemotaxis

72
Q

How does a fever begin?

A

infection triggers lymphocytes to proliferate, producing cells that secrete interleukin-1.

73
Q

What is known as the internal fire-maker?

A

interleukin-1

74
Q

Fever indirectly counters microbial growth because higher body temperature causes the liver and spleen to sequester ______.

A

iron

75
Q

The third line of defense is _______

A

immunity or adaptive defense

76
Q

nonself molecules that can elicit an immune response are called:

A

antigens

77
Q

The two types of adaptive immune responses include:

A

cellular/humoral

78
Q

Eggs and sperm have the potential of being recognized as nonself. How is this prevented?

A

eggs and sperm are hidden away and protected by many layers.

79
Q

Antigens may be:

a. proteins
b. polysaccharides
c. glycoproteins
d. glycolipids
e. all of the above

A

e.

80
Q

Most effective antigens are:

a. large and complex
b. small and repeating

A

a.

81
Q

A small molecule that cannot by itself stimulate an immune response and thus combines with a larger one is called:

a. interleukin
b. interferon
c. complement
d. hapten
e. antigen

A

d. hapten

82
Q

Lymphocyte production begins _______.

A

before birth

83
Q

Where do thymocytes become T-lymphocytes?

A

thymus

84
Q

T lymphocytes can be found:

a. thymus
b. thoracic duct
c. spleen (white pulp)
d. all of the above

A

d.

85
Q

Lymphocytes that mature fully in the red bone marrow are called:

a. red lymphoctyes
b. B-lymphoctyes
c. T-lymphocytes
d. macrophages

A

b.

86
Q

The majority of circulating lymphocytes are ______ lymphocytes.

A

T

87
Q

B-cells are abundant in:

a. lymph nodes
b. spleen
c. bone marrow
d. intestinal lining
e. all of the above

A

all of the above

88
Q

A lymphocyte must be _______ before it can respond to an antigen.

A

activated

89
Q

T-cell activation requires that processed fragments of the antigen be attached to the surface of an ________.

A

antigen-presenting cell

90
Q

All of the following can act as antigen-presenting cells except:

a. reticular cells
b. dendritic cells
c. macrophages
d. B cells
e. T cells

A

e. t cells

91
Q

Macrophages will digest bacteria and display the bacterial antigens on the cell membrane near certain proteins called:

A

major histocompatibility complex

92
Q

MHC help T cells recognize that the newly formed antigen is _____

A

foreign

93
Q

Activated T cells interact directly with the APC, this cell to cell contact is called:

A

cellular immune response

94
Q

T cells also synthesize and secrete polypeptides called _________>

A

cytokines

95
Q

Polypeptides that enhance certain cellular responses to antigens:

A

cytokines

96
Q

Name the types of cytokines:

A

CSF, interferons, interluekins, tumor necrosis factor

97
Q

What stimulates bone marrow to produce lymphocytes?

A

colony-stimulating factors

98
Q

Helper T cell is:

A

activated when its antigen receptor combines with a displayed foreign antigen

99
Q

Once activated, the Helper T cell stimulates ______ (plasma cell) to produce antibodies.

A

B cell

100
Q

Another type of T cell is a cytotoxic T cell:

A

secrete perforins to lyse cells

101
Q

Memory T cells come from:

A

cytotoxic T cells

102
Q

Do memory T cells respond to initial exposure to a pathogen?

A

no, with subsequent exposures they turn back into cytotoxic T cells and attack pathogen

103
Q

The only type of T cell that attacks pathogens is the:

A

cytotoxic t cell

104
Q

______ cells help B-cells to proliferate by secreting cytokines.

A

Helper T cells

105
Q

B cells differentiate further into______, which secrete ______, also known as ______.

A

plasma cells, antibodies, immunoglobulins

106
Q

Body fluids carry antibodies, which react in various ways to destroy specific antigens. This response is called:

A

humoral immune response (humoral means fluid)

107
Q

A single type of B cell carries information to produce a single type of antibody, TRUE OR FALSE:

A

true

108
Q

B cells that don’t become plasma cells that secrete antibodies become:

A

memory B cells, similar to memory T cells

109
Q

Antibodies are soluble, globular proteins that constitute the ____ ______ fraction of plasma proteins.

A

gamma globulin

110
Q

Each antibody molecule consists of ______

A

4 amino acid chains

111
Q

How many major types of immunoglobulins are there?

A

5

112
Q

Which immunoglobulin is the most abundant?

A

G

113
Q

Immunoglobulin G is in _____. It is effective against _______.

A

plasma and tissue fluid.

bacteria, viruses and toxins,
also activates complement proteins

114
Q

Anti-Rh antibodies are what category of antibodies?

A

G

115
Q

Immunoglobulin A is in _______.

A

Exocrine gland secretions such as breast milk, tears, nasal fluid, gastric juices, bile and urine.

116
Q

T cells diminish only slightly with increasing age, and numbers of B cells not at all. True or False?

A

True