Chapter 2 Flashcards

1
Q

Protein

A

Bio-macromolecule made of amino acid chains folded into 3D shape

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2
Q

polypeptide:

A

Long chain of amino acids.Protein can be made up of one or many polypeptides

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3
Q

Proteome

A

All the proteins that are expresed by a cell or organism at one given time

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4
Q

Enzyme

A

Organic molecule(typically protein) that catalyses reactions.

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5
Q

Peptide hormone

A

Protein signalling molecule

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6
Q

Antibody

A

protein produced by plasma cells during adaptive immune response

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7
Q

Hydrophobic

A

Repels and insoluble to water

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8
Q

Hydrophilic

A

Tendency to be attracted to and dissolve in water

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9
Q

Monomer

A

building blocks of polymers

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10
Q

Polymer

A

large molecule made up of monomers

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11
Q

Condensation reaction

A

reaction where 2 monomers join to form a larger molecule,producing water

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12
Q

Peptide bond

A

Bond that keeps amino acids together.

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13
Q

Primary structure

A

refers to the sequence of amino acids in a polypeptide chain

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14
Q

Secondary structure

A

formation of alpha helixs, b-plated sheets and random coils

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15
Q

Tertiary structure:

A

Refers to the functional 3d shape of a polypeptide chain

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16
Q

Quaternitry structure:

A

:2 or more polypeptide chains

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17
Q

Nucleic acid:

A

Macramolecules (DNA and RNA),polymer made up of nucleotides

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18
Q

Nucleotide

A

monomer,makes up a nucleic acid

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19
Q

Messenger RNA-

A

:Carry genetic information from the nucleus to the ribosome

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20
Q

Transport RNA

A

RNA that recognises specific codons on the mRNA strand and adds the corresponding amino acid to the polypeptide chain, during translation.

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21
Q

Ribosomal RNA

A

RNA that is a key structural component of ribosomes, assembling proteins

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22
Q

Transcription

A

Sequence of DNA is used as a template to create complementary sequence of mRNA

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23
Q

Translation

A

mRNA sequence is read to produce a corresponding amino acid sequence to build a polypeptide chain

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24
Q

Triplet

A

sequence of 3 nucleotide in DNA that forms a amino acid

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25
Codon
Sequence of 3 nucleotides in m-RNA that forms an amino acid
26
Start codon
(AUG)
27
Stop codons
(UAA,UGA,UAG)
28
Universal
All living organisms use the same codons to code for amino acids
29
Degenerate
1 amino acid can be coded for by many different codons
30
Unambiguous
Only 1 codon can code for 1 amino acid
31
Non-overlapping
each codon must be read individually
32
Regulatory genes
genes that produced proteins that have the ability to oppress or activate a gene
33
Structural genes
genes that are responsible for producing proteins that are involved in the structure or function of a cell
34
Promoter
region to which RNA polymerase binds in transcription
35
RNA polymerase
Enzyme responsible for constructing a pre-mRNA sequence from a dna sequence during transcription
36
Enzyme
helps catalyze a reaction
37
TATA box
a type of promoter region
38
Introns (only in eukaryotes):
non-coding regions
39
Exons:
regions of gene that code
40
Operator (prokaryotes):
where the repressor binds, alters transcription
41
Repressor protein
Protein coded for by regulatory protein, that prevents gene expression
42
Gene expression
process of reading information stored within a gene to create a functional protein
43
Leader region
segment on DNA or RNA that immediately proceeds the coding regio
44
Transcription factor
proteins that bind to promoter region and control the functioning of RNA polymerase
45
Alternative splicing
:Process where different exons may be spliced,resulting in a single gene producing multiple different mRNA strands
46
Anticodon
- sequence of three nucleotides on tRNA molecule (translation)
47
Exocytosis
type of bulk transport that moves large substances out of a cell
48
Trp operon
found within bacteria codes for tryptophan
49
Trp operon repression:
where repressor proteins bind to operon and stop the transcription of the tryptophan protein
50
Conformational change
A change of shape in the 3 dimensial shape of protein
51
Attenuator region:
part of the leader region within the trp operon that allows for attenuation
52
ribosome
site of protein synthesis
53
vesicle
a small fluid-field organelle enclosed in in a phospholipid membrane that transports substances around the cell
54
Rough endoplasmic reticulum
folds and transports proteins
55
Transport vesicle
transports proteins
56
Golgi apparatus
modifies and packages proteins
57
Secretory vesicle
transports proteins
58
Substrate
reactant of a reaction catalyzed by an enzyme
59
Reactant
molecule that undergoes a transformation into a product.When enzymes are involved the reactant is called the substrate
60
Active site
site on enzyme that the substrate binds to
61
Reversible inhibition
enzyme inhibition that involves weaker bonds that can be overcome
62
Irreversible inhibition
enzyme inhibition that cannot be brocken
63
Biochemical pathway:
a series of enzyme-catalysed biochemical reactions in which the product of one reaction becomes the substrate of the next reaction
64
cofactor
any organic or inorganic molecule that assists enzyme function
65
ATP
Adenine triphosphate, a high energy molecule, provides energy for cellular processes