Chapter 20 diseases Flashcards

1
Q

what causes bacterial meningitis?

A

Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae, Listeria monocytogenes, Streptococcus aglactiae

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2
Q

what causes meningococcal meningitis?

A

Neisseria meningitidis

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3
Q

what causes pneumococcal meningitis?

A

streptococcus pneumoniae

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4
Q

what causes viral meningitis?

A

Members of the genus Enterovirus of the family Picornaviridae

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5
Q

characteristics of Neisseria meningitidis?

A

gram negative diplococcus, it is not motile, meningococcus, has fimbriae

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6
Q

characteristics of Streptococcus pneumoniae?

A

Gram positive coccus; usually in pairs
>93 different strains

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7
Q

characteristics of Members of the genus Enterovirus of the family Picornaviridae?

A

Very small, nonenveloped, RNA viruses

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8
Q

reservoirs of the types meningitis?

A

humans

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9
Q

bacterial meningitis mode of transmission?

A

Droplet transmission and carriers

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10
Q

meningococcal meningitis mode of transmission?

A

Respiratory droplets to those who have prolonged contact with a patient

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11
Q

pneumococcal meningitis mode of transmission?

A

direct contact with respiratory secretions

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12
Q

viral meningitis mode of transmission?

A

-Fecal contamination of food, water, or hands
-Respiratory secretions

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13
Q

bacterial meningitis portals of entry?

A

Lungs, sinuses, or inner ear via the blood

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14
Q

Meningococcal meningitis portals of entry?

A

Lungs, sinuses, or inner ear via the blood

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15
Q

Pneumococcal meningitis portals of entry?

A

Normal microbiome of throat that opportunistically grow in the lungs, sinuses, and middle ear and move from these locations via the blood into the meninges

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16
Q

viral meningitis portals of entry?

A

ears, nose, throat

17
Q

virulence factors for bacterial meningitis?

A

12 serogroups have been identified (A, B, C, W, X, and Y cause epidemics)

18
Q

virulence factors for meningococcal meningitis?

A

Polysaccharide capsule, Lip oligosaccharide
-fimbriae
-all virulence factors enable bacteria to attach to human cells

19
Q

virulence factors for pneumococcal meningitis?

A

Polysaccharide capsule, Secretory IgA protease, Pneumolysin, and Phosphorylcholine

20
Q

how does bacterial meningitis affect the body?

A

Bacteria are somewhat protected from phagocytosis of of their capsules and they metabolize glucose in the CSF

21
Q

how does meningococcal meningitis affect the body?

A

the bacteria infect the lining of then brain and spinal cord which causes swelling

22
Q

how does viral meningitis affect the body?

A

it kills target cells in Gi or lungs, Grains access to blood, Spreads to the lymph organs, then affect the brain by killing the cells in the meninges

23
Q

Signs and Symptoms of bacterial meningitis?

A

-high fever, inflammation
-inflamed cranial meninges produce severe headache, nausea, vomiting, pain, loss of brain functions leading to drowsiness, confusion, fretfulness, or irritability
-stiff neck
-encephalitis (deafness, blindness, coma, death

24
Q

Signs and Symptoms of meningococcal meningitis?

A

Dramatic increase in WBC and CSF (milky shite in color)
Petechial rash

25
Q

Signs and Symptoms of pneumococcal meningitis?

A

high fever, stiff neck, chills, nausea and vomiting, mental changes, agitation, an intense headache, sensitivity to light, loss of consciousness or semi-consciousness, rapid breathing, arching of the head and neck backward

26
Q

Signs and Symptoms of viral meningitis?

A

Fever, stiff neck, severe headache, drowsiness, confusion, nausea, and vomiting
“worst headache of my life”
Skin rash, sore throat, and colds
DEATH IS RARE

27
Q

Epidemiology of meningococcal meningitis?

A

carriage rates highest in older children and young adults
-only type of bacterial meningitis that becomes epidemic

28
Q

Epidemiology of pneumococcal meningitis?

A

-Is in mouths and throats of 75% of pts. Without causing harm
-elderly and children

29
Q

Epidemiology of viral meningitis?

A

Enteroviruses are common and contagious.
Summer than fall
Stable in the environment and can survive in chlorinated swimming pools
Neonates at greatest risk

30
Q

Diagnosis of bacterial meningitis?

A

Diagnosis on basis of symptoms and on culturing bacteria from CSF following a spinal tap
Serological tests can demonstrate presence of antibodies

31
Q

Diagnosis of meningococcal meningitis?

A

spinal tap

32
Q

Diagnosis of viral meningitis?

A

Characteristic signs and symptoms of meningitis without Prescence of bacteria in CSF

33
Q

treatment of bacterial meningitis?

A

Medical emergency
Treatment with a variety of IV administered antimicrobial drugs

34
Q

treatment of viral meningitis?

A

No specific treatment
Bed rest, plenty of fluids, and meds to relieve fever and headache

35
Q

prevention of meningococcal meningitis?

A

Meningococcal conjugate vaccine (MCV4)-Menveo, Menactra
Menb Vaccine (Bexsero and Trumenba)

36
Q

prevention of pneumococcal meningitis?

A

Pneumococcal polysaccharide vaccine-pneumovax
-pneumococcal conjugate vaccine (PCV15 and PCV20)

37
Q

prevention of viral meningitis?

A

Hard to prevent.
Frequent handwashing, avoid crowded swimming pools, and refrain from touching mouth nose, or eyes with contaminated hands