Chapter 20 diseases Flashcards
(37 cards)
what causes bacterial meningitis?
Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae, Listeria monocytogenes, Streptococcus aglactiae
what causes meningococcal meningitis?
Neisseria meningitidis
what causes pneumococcal meningitis?
streptococcus pneumoniae
what causes viral meningitis?
Members of the genus Enterovirus of the family Picornaviridae
characteristics of Neisseria meningitidis?
gram negative diplococcus, it is not motile, meningococcus, has fimbriae
characteristics of Streptococcus pneumoniae?
Gram positive coccus; usually in pairs
>93 different strains
characteristics of Members of the genus Enterovirus of the family Picornaviridae?
Very small, nonenveloped, RNA viruses
reservoirs of the types meningitis?
humans
bacterial meningitis mode of transmission?
Droplet transmission and carriers
meningococcal meningitis mode of transmission?
Respiratory droplets to those who have prolonged contact with a patient
pneumococcal meningitis mode of transmission?
direct contact with respiratory secretions
viral meningitis mode of transmission?
-Fecal contamination of food, water, or hands
-Respiratory secretions
bacterial meningitis portals of entry?
Lungs, sinuses, or inner ear via the blood
Meningococcal meningitis portals of entry?
Lungs, sinuses, or inner ear via the blood
Pneumococcal meningitis portals of entry?
Normal microbiome of throat that opportunistically grow in the lungs, sinuses, and middle ear and move from these locations via the blood into the meninges
viral meningitis portals of entry?
ears, nose, throat
virulence factors for bacterial meningitis?
12 serogroups have been identified (A, B, C, W, X, and Y cause epidemics)
virulence factors for meningococcal meningitis?
Polysaccharide capsule, Lip oligosaccharide
-fimbriae
-all virulence factors enable bacteria to attach to human cells
virulence factors for pneumococcal meningitis?
Polysaccharide capsule, Secretory IgA protease, Pneumolysin, and Phosphorylcholine
how does bacterial meningitis affect the body?
Bacteria are somewhat protected from phagocytosis of of their capsules and they metabolize glucose in the CSF
how does meningococcal meningitis affect the body?
the bacteria infect the lining of then brain and spinal cord which causes swelling
how does viral meningitis affect the body?
it kills target cells in Gi or lungs, Grains access to blood, Spreads to the lymph organs, then affect the brain by killing the cells in the meninges
Signs and Symptoms of bacterial meningitis?
-high fever, inflammation
-inflamed cranial meninges produce severe headache, nausea, vomiting, pain, loss of brain functions leading to drowsiness, confusion, fretfulness, or irritability
-stiff neck
-encephalitis (deafness, blindness, coma, death
Signs and Symptoms of meningococcal meningitis?
Dramatic increase in WBC and CSF (milky shite in color)
Petechial rash