Chapter 4: Immune Tolerance

Question 1

What is the lymphoid system?

Answer 1

The tissues involved in the production and circulation of lymphocytes (B and T cells)

Question 2

What are the 2 lymphoid tissues?

Answer 2

the Central (primary lymphoid tissues and the Peripheral (secondary) lymphoid tissues

Question 3

What is included in the central lymphoid tissues?

Answer 3

The Bone Marrow for B cells and the Thymus for T cells

Question 4

What is the function of the central LT?

Answer 4

Generate lymphocytes

Question 5

What is the primary function of the Peripheral LT?

Answer 5

Expose lymphocytes to antigen, where adaptive immune responses are initiated

Question 6

What is included in the Peripheral LT?

Answer 6

The lymph nodes, spleen, and Mucosal-associated lymphoid tissues

Question 7

What does the activation of helper T cell require?

Answer 7

1. Antigen on MHC II

2. Costimulatory Signals

Question 8

When do dendritic cells express co stimulatory signals

Answer 8

When it has been activated by pattern recognition receptors that indicate the presence of an infection