Exam Two: Cytokines Flashcards
(20 cards)
What is the job of Chemical Messengers aka Signals?
They perform the job of relaying messages between cells. (example Insulin and Adrenaline)
What is the function of a cytokine?
to allow different immune cells to communicate with one another.
What is the function of a signal transduction pathway?
To induce the correct response from the message
What is an immune mediator?
A chemical signal in immunity ( protein, lipid, or carbohydrates)
What is the formal definition of a cytokine?
protein that act as chemical messengers in the immune system that have specific receptors
What is the formal definition of Chemokines?
They are a subset of Cytokines, that function as a chemoattractant. `
What is the function of a chemoattractant?
They attract white blood cells to a particular location
List the Primary Cytokines:
IL -1
IL-6
TNF
List the Cytokines associated with cell division:
IL- 2 and IL 3
What is the function of Interleukins?
They send messages between white blood cells
What is the function of Interferons?
Produced by virus-infected cells that interfere with infection of other cells = limit the spread of viruses
What is the Function of Tumor necrosis factor and Transforming growth factor beta?
Molecules that act on cancer cells but also play a essential role in the immune system.
TH1 T cell subset is induced by which Interferon?
Induced by Interferon gamma (y)
TH2 subset is induced by which Interleukins?
Interleukin-4 and 5
TReg cells are induced by what?
It induced by TGFB and IL-10
What is Interleukin-2
General T cell growth factor
needed for clonal amplification
What is the type of response in the innate immune system that responds to viral infections?
The Interferon Response
Production of Type I interferons and NK cells is involved in which response of the immune system?
The innate Immune response
What Receptor recognizes Viral RNA in the cell?
RIG - 1 which stimulates cytokine and interferon production
Recognize invading germs
What is the Febrile Response?
A fever, which is just an increase in body temperature
