Exam Two: Inflammation Flashcards
(23 cards)
What are the classical definitions of inflammation?
- Heat and Rashes
- Swelling
- Pain
In inflammation what causes Heat and Redness and what does it mean?
Vasodilation- widening of the blood vessels
Heat and Redness are a side-effect of increased blood flow
What is the technical term for Swelling?
Oedema
What causes oedema in inflammation?
Leaky blood vessels that allow leukocytes to cross into the tissue.
Pain is what to the body?
A warning signal that there is a problem
What is the technical definition for inflammation?
Recruitment of cells that cause damage(injury) as a side effect of fighting infection.
Is inflammation a long or short term response?
It is meant to be a short term response
Why must a inflammation response be limited?
Can cause tissue damage that becomes pathological
What is an inflammatory disease?
Result of a persistent infection or injury that cannot be resolved
Match the disorder with the organ it effects:
- Nephritis
- Arthritis
- Dermatitis
- Hapatitis
- Vasculitis
- Bronchitis
- Kidney
- Joints
- Skin
- Liver
- Blood Vessels
- Airway of the lung
Why can inflammation be cause by an infection and/or injury?
They come as a package deal. Infection is the innate immune response and injury is the wound healing response.
What is Thrombosis?
It is a wound healing response of blood clotting
What is fibrosis?
condition where the process of damaged matrix is degraded and fibrin fills in the gaps is uncontrolled. This leads to scarring that destroys tissue
Are the classic symptoms of inflammation observed in chronic conditions?
No
What is Pulmonary Emphysema
Damage to tissue caused by persistent inflammatory response without an infection
What is Septic Shock
Inflammatory disease that occurs all throughout the body instead of local
What is Atherosclerosis?
Inflammatory disease that was though to be non inflammatory
What is Autoinflammatory Disorders?
Genetically inherited disorder
Give rise to the symptoms of severe infection even when there isn’t one
What does Systemic represent in light of immune response?
Means the response occurs throughout the body
What are Atherosclerotic Plaques made of?
Plaques are caused by the recruitment of monocytes that cannot pass through the artery
What is an Atherosclerotic Plaque
Sites of leukocyte recruitment and fibrosis that result in tissue damage and is a form of chronic inflammation
What is an Autoinflammatory Disease?
Inappropriate expression of chemical messenger molecules called primary cytokines
What is the function of a cytokine?
They initiate and amplify the inflammatory response
