Chapter 4/Movement of Molecules Across Cell Membranes Flashcards

1
Q

Movement of molecules from one location to
another as a result of their random thermal
motion

A

Diffusion

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2
Q

Magnitude of net flux influenced by:

A

-Temperature
– Mass of the solute
– Surface area
– Medium

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3
Q

Diffusion time _ in proportion to the _ of the distance over which the
molecules diffuse

A

increases , square

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4
Q

Limited _
* Diffusion is _over a long distance

A

not effective, distance

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5
Q

Membranes considerably slow the diffusion of
molecules

A

across their surfaces

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6
Q

O2, CO2, fatty acids, steroid hormones
rapidly through membranes.

A

diffuse

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7
Q

Polar molecules __readily through
membranes.

A

do not, diffuse

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8
Q

Ions (Na+, K+, Cl–, Ca2+) use __ to diffuse in and out of the ;\;’

A

protein channels, cell

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9
Q

channels form

A

integral membrane protein

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10
Q

Specificity of channel is determined by .

A

pore
size, charge, and binding sites

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11
Q

Separation of electrical charges across the
plasma membrane

A

Membrane potential

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12
Q

Diffusion of ions influenced by

A

concentration
and membrane potential

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13
Q

Channels are regulating

A

to control movement
of ions in and out of the cell

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14
Q

Type of gated channels

A

-Ligand-gated
– Voltage-gated
– Mechanically gated

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15
Q

Molecules that are too large and charged

A

Mediated Transport Systems

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16
Q

Protein transporters bring these molecules

A

into and out of the cell

17
Q

Magnitude of net flux influenced by

A

-Solute concentration
– Affinity of transporters for solute
– Number of transporters
– Rate of conformational change

18
Q

Facilitated diffusion

A

-Net flux from high to low concentration
– Uses transporter to move solute across membrane

19
Q

-Uses energy
– Moves solute against the concentration gradient

A

Active transport

20
Q

ATPase: hydrolysis of ATP

A

Use ATP directly

21
Q

-Found in every cell
– Helps establish and maintain membrane potential

A

Na+/K+-ATPase

22
Q

Use electrochemical gradient across
membrane as energy source

A

Secondary Active Transport

23
Q
  • Ion
    – Cotransported molecule
A

Two binding sites

24
Q

move
molecules in same
direction

A

Cotransporters

25
move molecules in opposite directions
counter transporter
26
Net diffusion of water across a membrane
Osmosis
27
Facilitated by aquaporins
Osmosis
28
29
of aquaporins varies among cell types
Osmosis
30
The total solute concentration of a solution
Osmolarity
31
1 osmol = 1 mol of solute particles
Osmolarity
32
Higher osmolarity means lower water concentration
Osmolarity
33
Movement of molecules into the cell via vesicles
Endocytosis
34
3 general types: endocytosis
-Pinocytosis – Phagocytosis – Receptor mediated endocytosis
35
Movement of molecules out of the cell via vesicles
exocytosis
36
Replace portions of the plasma membrane that endocytosis removed – Add new membrane components to plasma membrane – Provides a pathway for secretion of membrane- impermeable molecules
exocytosis
37
diffusion between adjacent cells. – Limited by tight junctions
Paracellular pathway
38
movement through the cell
Transcellular pathway