Chapter 4 - Source Drug

Question 1

______ Chemical agent that stimulate or inhibit existing cell function but not creat new one

Answer 1

Drug

Question 2

Source of drug

Answer 2

1. Natural source
2. Semisynthetic source
3. synthetic
4. Biosynthetics

Question 3

1. Natural synthetic include:

Answer 3

1. Plant
2. Animal
3. Microbiological
4. Minerals

Question 4

A. Plant source - Atropin drug extract from

Answer 4

Atropa belladonna

Question 5

A. Plant source - Morphine drug extract from

Answer 5

Papavarum somniferum

Question 6

A. Plant source - Nicotine drug extract from

Answer 6

Tobacco

Question 7

A. Plant source - Digoxin drug extract from

Answer 7

Digitalis plant - open sodium channel

Question 8

B. Animals source - Hypurine extract from

Answer 8

Liver secretion

Question 9

_______ Many life-saving drugs are obtained from fungi, moulds and bacteria

Answer 9

Microbiological drug

Question 10

C. Source of microbiological - penicillin drug extract from

Answer 10

Penicillium notatum

Question 11

________ used to prepare drugs when the synthesis of drugs complex molecules, expensive and uneconomical or when the natural sources may yield impure compounds.

Answer 11

Semisynthetic source

Question 12

Semisynthetic source

Answer 12

It is the modification of a natural drug by changing its chemical structure

Question 13

Semisynthetic source

Answer 13

• Penicillin -> Tetracycline
• immature insulin -> insulin

Question 14

Synthetic

Answer 14

It is the drug that has been completely synthesized in the laboratory.

Question 15

Synthetic source:

Answer 15

• aspirin
• antihistamine

Question 16

New source

Answer 16

New field which is being developed by mixing discoveries from molecular biology, recombinant DNA technology, DNA alteration, gene splicing, immunology and immunopharmacology.

Question 17

Examples:

Answer 17

• Coronavirus- replicate unit vaccine (mRNA)
• Hepatitis B vaccine
• Human insulin

Question 18

Uses of drug:

Answer 18

1. Treatment of disease
2. Diagnostic
3. Growth promoter
4. Prevention of disease ( prophylactic )
5. Metaphylactic

Question 19

Metaphylactic:

Answer 19

It is the preventive treatment given to farm animals after the occurrence of disease case within the group.

Question 20

__________ Active ingredient obtained from any source should be put in proper dosage forms to be absorbed (synthesis drug in lab)

Answer 20

Pharmaceutical

Question 21

______ it is the action of body toward drug , it consist 4 process: absorption, distribution, metabolism, excretion

Answer 21

Pharmacokinetics

Question 22

______ it is effct of drug on body

Answer 22

Pharmacodynamic

Question 23

_______ it deals with use of drug diagnosis, treatment, prevention

Answer 23

Pharmacotherpeutic