Chapter 47 Lower Gastrointestinal Problems Part 2 Flashcards
(472 cards)
What is toxic megacolon?
A condition associated with inflammatory bowel disease (IBD), particularly ulcerative colitis, that increases the risk for perforation and may require emergency colectomy.
What complications can occur in Crohn’s disease?
Complications include perineal abscesses and fistulas, which occur in up to a third of patients.
How does CDI relate to IBD?
Clostridium difficile infection (CDI) increases in frequency and severity in patients with inflammatory bowel disease.
What is the risk associated with IBD regarding cancer?
IBD is related to an increased risk for colorectal cancer (CRC) and small intestinal cancer in Crohn’s disease.
What systemic complications can arise from IBD?
Complications can include multiple sclerosis, ankylosing spondylitis, malabsorption, liver disease (primary sclerosing cholangitis), and osteoporosis.
How often should patients with IBD undergo bone density scans?
Patients should have a bone density scan at baseline and every 2 years.
What diagnostic studies are important for IBD?
Diagnostic studies include ruling out diseases with similar symptoms, stool examination, imaging studies, and colonoscopy.
What are common clinical manifestations of IBD?
Common manifestations include diarrhea, weight loss, abdominal pain, fever, and fatigue.
What symptoms are associated with Crohn’s disease?
Symptoms include diarrhea, cramping abdominal pain, weight loss due to malabsorption, and occasional rectal bleeding.
What symptoms are characteristic of ulcerative colitis (UC)?
Characteristic symptoms include bloody diarrhea and varying degrees of abdominal pain.
What is the stool output in mild UC?
In mild disease, diarrhea may consist of no more than 4 semiformed stools daily containing small amounts of blood.
What defines moderate disease in UC?
In moderate disease, the patient has up to 10 stools per day, increased bleeding, and systemic symptoms such as fever and malaise.
What are the symptoms of severe UC?
Severe symptoms include bloody diarrhea occurring 10 to 20 times a day, fever, rapid weight loss, anemia, tachycardia, and dehydration.
What local complications can occur in IBD?
Local complications include hemorrhage, strictures, perforation, abscesses, fistulas, and Clostridium difficile infection.
What laboratory findings may indicate complications in IBD?
Findings may include iron deficiency anemia, high WBC count, electrolyte imbalances, hypoalbuminemia, and increased inflammatory markers.
What imaging studies are used for diagnosing IBD?
Imaging studies include double-contrast barium enema, small bowel series, transabdominal ultrasound, CT, and MRI.
What is the goal of treatment for IBD?
Goals include resting the bowel, controlling inflammation, correcting malnutrition, providing symptomatic relief, and improving quality of life.
Is there a cure for IBD?
No, there is no cure for IBD; treatment focuses on managing inflammation and maintaining remission.
What is the preferred treatment for Crohn’s disease due to high recurrence rates?
Drugs are the preferred treatment due to high recurrence rates after surgical treatment.
What indicates the need for hospitalization in IBD patients?
Hospitalization is needed if the patient does not respond to drug therapy, the disease is severe, or complications are suspected.
What is the goal of drug treatment in IBD?
To induce and maintain remission.
Name the five major classes of drugs used in IBD treatment.
- Aminosalicyclates
- Antimicrobials
- Corticosteroids
- Immunomodulators
- Biologic therapies
What factors influence drug choice in IBD treatment?
Location and severity of inflammation.