Chapter 5 Pediatric Considerations

Question 1

Neonate

Answer 1

Birth at 38 or more weeks gestation to 27 days

Question 2

Infant/toddler

Answer 2

28 days to 23 months

Question 3

Children

Answer 3

24 months to 11 years

Question 4

Adolescent

Answer 4

12 years the 18 years

Question 5

Neonate absorption

Answer 5

Intestinal surface area in neonates does not reach that old an adults until 20 weeks so the absorption rate is decreased.
Inadequate amount of bile salts and pancreatic enzymes

Question 6

Infants and young children absorption

Answer 6

Skin is thinner and so is the BMI allowing for a higher rate of absorption and toxicity of drugs

Question 7

Neonates distribution

Answer 7

75% water instead of 60%
Allowing for a less concentrated drug
Have a lower amt of receptors and protein binders causing more free drugs being retained
BBB allows drugs to move across fairly easily

Question 8

Neonates excretion

Answer 8

30% of adults GFR. By 12 months It reaches adult levels

Question 9

Infant drug form

Answer 9

Liquids in small volumes

Question 10

Children 2-5 years old form

Answer 10

Liquids, effervescent tablets dispersed in liquids, sprinkled on food

Question 11

Children 6-11 years form

Answer 11

Solids

Question 12

Adolescents drug form

Answer 12

Adult dosage, solids