Chapter 6 Flashcards

1
Q

The transmission of genes close to one another on the same chromosome violates which of Mendels laws

A

The law of segregation

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2
Q

What is synteny

A

When two or more genes are located on the same chromosome and are physically linked

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3
Q

What is genetic linkage

A

When genes close together on a chromosome tend to be transmitted as a unit which influences inheritance patterns

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4
Q

What causes genes that are far apart to independently assort

A

Crossing over

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5
Q

Linkage is altered during prophase one of meiosis due to crossing over. What do replicated sister chromatids associate as and what do non sister chromatids do

A

Bivalents
Non sister chromatids exchange dna segments
Crossing over may produce recombinant genotypes

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6
Q

In haploid cells what is true regarding linkage

A

They contain the same combination of alleles as the original chromosomes
The arrangement of linked alleles doesn’t alter in gametes
Without crossing over there can be no recombination

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7
Q

What is a non parental or recombinant cell

A

Haploid cells that contain a combo of alleles not found in the original chromosome

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8
Q

How are recombinant offspring produced

A

The exchange of dna between two homologous chromosomes during meiosis in one or both parents leading to new genetic material

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9
Q

According to one of Morgan’s hypothesis why might all three genes be inherited together

A

They are all on the X chromosome

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10
Q

What other major hypothesis did Morgan have

A

Crossing over results in new combos of alleles
The likelihood of crossing over depends on the distance between the two genes with a higher probability toward genes farther apart

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11
Q

What does each gene have

A

Its own unique locus

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12
Q

Why do we do genetic mapping

A

To determine the linear order of linked genes along the same chromosome

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13
Q

What is the map distance equation

A

Number of recombinant offspring divided by total number of offspring multiplied by 100

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14
Q

What is a test cross

A

An individual that is heterozygous for two or more genes is crossed to one that is homozygous recessive for the same genes

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15
Q

What can test cross data be used for

A

Estimating the distance between two genes
A test cross is expected to yield a maximum of only 50 percent recombinant offspring

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16
Q

What can multiple crossovers cause

A

A limit on measurable recommendation frequencies because the physical distance increases

17
Q

With a combo of traits in a double crossover what can we find out

A

Which gene is in the middle

18
Q

Why might you have a lower than expected value of crossovers

A

Positive interference

19
Q

What does a first cross over reduce

A

The probability that a second crossover will occur nearby

20
Q

What is mitotic recombination

A

When crossing over occurs during mitosis which leads to a new combo of alleles

21
Q

What might happen during mitotic recombination in early embryonic development

A

The daughter cells containing the recombinant chromosomes continue to divide and a patch of tissue with different characteristics results