Chapter 6 Flashcards

(41 cards)

1
Q

what are the stop codons

A

UAA
UAG
UGA

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2
Q

what is the initiation codon

A

AUG (MET) Methionine

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3
Q

discovered the relationship between 64 codons and the 20 amino acids was determined by experiments done mostly in the laboratories of _________ and ________ who shared the Nobel prize in 1968.

A

Marshall Nirenberg and H. Gobind Khorana

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4
Q

Poly G cannot be translated in vitro because it _________

A

folds up upon itself and therefore cannot be translated.

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5
Q

UUU
UUC
(F) (Phe)

A

Phenylalanine

Neutral, Nonpolar

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6
Q
CUU
CUC
CUA
CUG 
UUA
UUG
Leu (L)
A

Leucine

Neutral, Nonpolar

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7
Q

AUU
AUC
AUA
Ile (I)

A

Isoleucine

Neutral, Nonpolar

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8
Q

AUG

Met (M)

A

Methionine

Neutral, Nonpolar

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9
Q
GUU
GUC
GUA
GUG
Val (V)
A

Valine

Neutral, Nonpolar

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10
Q
UCU
UCC
UCA
UCG
Ser (S)
A

Serine

Neutral Polar

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11
Q
CCU
CCC
CCA
CCG
Pro (P)
A

Proline

Neutral Nonpolar

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12
Q
ACU
ACC
ACA
ACG
Thr (T)
A

Theronine

Neutral Polar

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13
Q
GCU
GCC
GCA
GCG
Ala (A)
A

Alanine

Neutral, Nonpolar

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14
Q

UAU
UAC
Tyr (Y)

A

Tyrosine

Neutral Polar

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15
Q

CAU
CAC
His (H)

A

Histidine

Basic

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16
Q

CAA
CAG
Gln (Q)

A

Glutamine

Neutral, Polar

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17
Q

AAU
AAC
Asn (N)

A

Asparagine

Neutral Polar

18
Q

AAA
AAG
Lys (K)

19
Q

GAU
GAC
Asp (D)

A

Aspartic Acid

Acidic

20
Q

GAA
GAG
Glu (E)

A

Glutamic Acid

Acid

21
Q

UGU
UGC
Cys (C)

A

Cysteine

Neutral Polar

22
Q

UGG

Trp (W)

A

Tryptophan

Neutral Nonpolar

23
Q
CGU
CGC
CGA
CGG
AGA
AGG
Arg (R)
A

Arginine

Basic

24
Q

AGU
AGC
Ser (S)

A

Serine

Neutral Polar

25
``` GGU GGC GGA GGG Gly (G) ```
Glycine | Neutral Nonpolar
26
All genetic code is degenerate with two exceptions which are AUG and UGG
METHIONINE AND TRYPTOPHAN
27
The addition or deletion of base pairs in DNA sequencing causes ________ ______ mutations.
frame shift
28
When do polypeptides fold contranslationally?
They fold during the translation process rather than after they are released from the ribosome.
29
is a high-molecular-weight, nitrogen-containing orgainc compound of complex shape and composition.
protein
30
a protein consists of one or more macromolecular subunits called
polypeptides
31
polypeptides are composed of small building blocks called
amino acids.
32
bonds that are created from a covalent bond between a carboxyl group from one amino acid and an amino group from another amino acid
peptide bond
33
The tertiary structure of a polypeptide is directly determined by the distribution of the _______ _____ along the chain.
R groups
34
how many codes make up the genetic code
64
35
another name for stop codons are
nonsense codons, and chain-terminating codons.
36
The wobble hypothesis was proposed by
Francis Crick
37
The recognition of the tRNA by the mRNA codon was proved by ________
G. von Ehrenstein, B. Weisblum, and S. Benzer
38
Polypeptide synthesis takes place on
Ribosomes
39
In both prokaryotes and eukaryotes _________ consist of two unequally sized subunits- the large and small each of which consists of a complex between RNA molecules and proteins
ribosomes
40
all amino acids have the same common structure except
proline
40
Neutral non polar
Trp (W)